3-D nanoporous gold thin film for the simultaneous electrochemical determination of dopamine and ascorbic acid

被引：76

作者：

El-Said, Waleed Ahmed ^{[2
]}

Lee, Jin-Ho ^{[1
]}

Oh, Byung-Keun ^{[1
,2
]}

Choi, Jeong-Woo ^{[1
,2
]}

机构：

[1] Sogang Univ, Dept Chem & Biomol Engn, Seoul 121742, South Korea

[2] Sogang Univ, Interdisciplinary Program Integrated Biotechnol, Seoul 121742, South Korea

来源：

ELECTROCHEMISTRY COMMUNICATIONS | 2010年 / 12卷 / 12期

关键词：

Nanoporous film; Differential pulse voltammetry; Human serum; Dopamine; MODIFIED ELECTRODE; POROUS LAYERS; CARBON;

D O I：

10.1016/j.elecom.2010.10.015

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

In this study, we demonstrated a novel fabrication method of three dimensional nanoporous gold thin film (NPGF) onto gold (Au) substrate using electrochemical deposition method. Scanning electron microscope (SEM) investigation reveals the formation of highly-ordered pores, approximately 30 nm in diameter and 150 nm thick. The NPGF-modified electrode shows a linear range (0.1-40 mu M) for dopamine detection in the presence of ascorbic acid. The electrochemical measurements of mixtures of dopamine, ascorbic acid, and uric acid in human serum sample for real sample applications was also investigated based on differential pulse voltammetry (DPV) technique. These high sensitivity and selectivity features of the proposed NPGF biosensor offer great promise for real sample biosensor application. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：1756 / 1759

页数：4

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