British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

被引：1589

作者：

Lamb, Christopher Andrew ^{[1
,2
]}

Kennedy, Nicholas A. ^{[3
,4
]}

Raine, Tim ^{[5
]}

Hendy, Philip Anthony ^{[6
,7
]}

Smith, Philip J. ^{[8
]}

Limdi, Jimmy K. ^{[9
,10
]}

Hayee, Bu'Hussain ^{[11
,12
]}

Lomer, Miranda C. E. ^{[12
,13
]}

Parkes, Gareth C. ^{[14
,15
]}

Selinger, Christian ^{[16
,17
]}

Barrett, Kevin J. ^{[18
]}

Davies, R. Justin ^{[5
,19
]}

Bennett, Cathy ^{[20
,21
]}

Gittens, Stuart ^{[22
]}

Dunlop, Malcolm G. ^{[23
,24
]}

Faiz, Omar ^{[7
,25
]}

Fraser, Aileen ^{[26
]}

Garrick, Vikki ^{[27
]}

Johnston, Paul D. ^{[28
]}

Parkes, Miles ^{[5
]}

Sanderson, Jeremy ^{[12
,13
]}

Terry, Helen ^{[28
]}

Gaya, Daniel R. ^{[29
,30
]}

Iqbal, Tariq H. ^{[31
,32
]}

Taylor, Stuart A. ^{[33
,34
]}

Smith, Melissa ^{[35
,36
]}

Brookes, Matthew ^{[37
,38
]}

Hansen, Richard ^{[27
,30
]}

Hawthorne, A. Barney ^{[39
]}

机构：

[1] Newcastle Univ, Newcastle Upon Tyne, Tyne & Wear, England

[2] Newcastle Tyne Hosp NHS Fdn Trust, Newcastle Upon Tyne, Tyne & Wear, England

[3] Royal Devon & Exeter NHS Fdn Trust, Exeter, Devon, England

[4] Univ Exeter, Exeter, Devon, England

[5] Cambridge Univ Hosp NHS FoundationTrust, Cambridge, England

[6] Chelsea & Westminster Hosp NHS Fdn Trust, London, England

[7] Imperial Coll London, London, England

[8] Royal Liverpool & Broadgreen Univ Hosp NHS Trust, Liverpool, Merseyside, England

[9] Pennine Acute Hosp NHS Trust, Manchester, Lancs, England

[10] Univ Manchester, Manchester, Lancs, England

[11] Kings Coll Hosp NHS Fdn Trust, London, England

[12] Kings Coll London, London, England

[13] Guys & St Thomas NHS Fdn Trust, London, England

[14] Barts Hlth NHS Trust, London, England

[15] Barts & London Queen Marys Sch Med & Dent, London, England

[16] Leeds Teaching Hosp NHS Trust, Leeds, W Yorkshire, England

[17] Univ Leeds, Leeds, W Yorkshire, England

[18] New Rd Surg, Rickmansworth, England

[19] Univ Cambridge, Cambridge, England

[20] Systemat Res Ltd, Quorn, England

[21] RCSI, Dublin, Ireland

[22] ECD Solut, Bridgetown, Barbados

[23] Univ Edinburgh, Edinburgh, Midlothian, Scotland

[24] Western Gen Hosp, Edinburgh, Midlothian, Scotland

[25] St Marks Hosp, Harrow, Middx, England

[26] Univ Hosp Bristol NHS Fdn Trust, Bristol, Avon, England

[27] Royal Hosp Children Glasgow, Glasgow, Lanark, Scotland

[28] Crohns & Colitis UK, Hatfield, Herts, England

[29] Glasgow Royal Infirm, Glasgow, Lanark, Scotland

[30] Univ Glasgow, Glasgow, Lanark, Scotland

[31] Queen Elizabeth Hosp Birmingham NHSFdn Trust, Birmingham, W Midlands, England

[32] Univ Birmingham, Birmingham, W Midlands, England

[33] UCL, London, England

[34] Univ Coll London Hosp NHS Fdn Trust, London, England

[35] Brighton & Sussex Univ Hosp NHS Trust, Brighton, E Sussex, England

[36] Brighton & Sussex Med Sch, Brighton, E Sussex, England

[37] Royal Wolverhampton NHS Trust, Wolverhampton, England

[38] Univ Wolverhampton, Wolverhampton, England

[39] Univ Hosp Wales, Cardiff, Wales

来源：

GUT | 2019年 / 68卷

关键词：

POUCH-ANAL ANASTOMOSIS; ACTIVE ULCERATIVE-COLITIS; QUALITY-OF-LIFE; CLOSTRIDIUM-DIFFICILE INFECTION; ANTI-TNF THERAPY; RANDOMIZED CLINICAL-TRIAL; PERIANAL CROHNS-DISEASE; TERM-FOLLOW-UP; INTRAABDOMINAL SEPTIC COMPLICATIONS; FECAL MICROBIOTA TRANSPLANTATION;

D O I：

10.1136/gutjnl-2019-318484

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease. Both represent chronic inflammation of the gastrointestinal tract, which displays heterogeneity in inflammatory and symptomatic burden between patients and within individuals over time. Optimal management relies on understanding and tailoring evidence-based interventions by clinicians in partnership with patients. This guideline for management of inflammatory bowel disease in adults over 16 years of age was developed by Stakeholders representing UK physicians (British Society of Gastroenterology), surgeons (Association of Coloproctology of Great Britain and Ireland), specialist nurses (Royal College of Nursing), paediatricians (British Society of Paediatric Gastroenterology, Hepatology and Nutrition), dietitians (British Dietetic Association), radiologists (British Society of Gastrointestinal and Abdominal Radiology), general practitioners (Primary Care Society for Gastroenterology) and patients (Crohn's and Colitis UK). A systematic review of 88 247 publications and a Delphi consensus process involving 81 multidisciplinary clinicians and patients was undertaken to develop 168 evidence- and expert opinion-based recommendations for pharmacological, non-pharmacological and surgical interventions, as well as optimal service delivery in the management of both ulcerative colitis and Crohn's disease. Comprehensive up-to-date guidance is provided regarding indications for, initiation and monitoring of immunosuppressive therapies, nutrition interventions, pre-, peri- and postoperative management, as well as structure and function of the multidisciplinary team and integration between primary and secondary care. Twenty research priorities to inform future clinical management are presented, alongside objective measurement of priority importance, determined by 2379 electronic survey responses from individuals living with ulcerative colitis and Crohn's disease, including patients, their families and friends.

引用

页码：S1 / S106

页数：106

共 1286 条

[1] Prevalence and Impact of Inflammatory Bowel Disease-Irritable Bowel Syndrome on Patient-reported Outcomes in CCFA Partners [J].

Abdalla, Maisa I. ;

Sandler, Robert S. ;

Kappelman, Michael D. ;

Martin, Christopher F. ;

Chen, Wenli ;

Anton, Kristen ;

Long, Millie D. .

INFLAMMATORY BOWEL DISEASES, 2017, 23 (02) :325-331

[2]

Abdallah J, 2013, INFLAMM BOWEL DIS S1, V19, pS46

[3] Ileitis in ulcerative colitis: Is it a backwash? [J].

Abdelrazeq, AS ;

Wilson, TR ;

Leitch, DL ;

Lund, JN ;

Leveson, SH .

DISEASES OF THE COLON & RECTUM, 2005, 48 (11) :2038-2046

[4] Higher Surgical Morbidity for Ulcerative Colitis Patients in the Era of Biologics [J].

Abelson, Jonathan S. ;

Michelassi, Fabrizio ;

Mao, Jialin ;

Sedrakyan, Art ;

Yeo, Heather .

ANNALS OF SURGERY, 2018, 268 (02) :311-317

[5] Corticosteroids and immunomodulators: Postoperative infectious complication risk in inflammatory bowel disease patients [J].

Aberra, FN ;

Lewis, JD ;

Hass, D ;

Rombeau, JL ;

Osborne, B ;

Lichtenstein, GR .

GASTROENTEROLOGY, 2003, 125 (02) :320-327

[6] Azithromycin found to be comparable to levofloxacin for the treatment of US travelers with acute diarrhea acquired in Mexico [J].

Adachi, JA ;

Ericsson, CD ;

Jiang, ZD ;

DuPont, MW ;

Martinez-Sandoval, F ;

Knirsch, C ;

DuPont, HL .

CLINICAL INFECTIOUS DISEASES, 2003, 37 (09) :1165-1171

[7] Association Between Serum Concentration of Infliximab and Efficacy in Adult Patients With Ulcerative Colitis [J].

Adedokun, Omoniyi J. ;

Sandborn, William J. ;

Feagan, Brian G. ;

Rutgeerts, Paul ;

Xu, Zhenhua ;

Marano, Colleen W. ;

Johanns, Jewel ;

Zhou, Honghui ;

Davis, Hugh M. ;

Cornillie, Freddy ;

Reinisch, Walter .

GASTROENTEROLOGY, 2014, 147 (06) :1296-+

[8] Bone, inflammation, and inflammatory bowel disease [J].

Agrawal M. ;

Arora S. ;

Li J. ;

Rahmani R. ;

Sun L. ;

Steinlauf A.F. ;

Mechanick J.I. ;

Zaidi M. .

Current Osteoporosis Reports, 2011, 9 (4) :251-257

[9] Relapse after withdrawal from anti-TNF therapy for inflammatory bowel disease: an observational study, plus systematic review and meta-analysis [J].

Ahmad, Tariq ;

Basavaraju, Umesh ;

Basquill, Catriona ;

Cameron, Fiona L. ;

Christodoulou, Christos ;

Cummings, Fraser ;

Ding, Nik S. ;

Fadra, Adam S. ;

Flanders, Lucy ;

Gaya, Daniel R. ;

Gooding, Ian ;

Gordon, John ;

Grieveson, Kay ;

Harris, Richard ;

Hart, Ailsa ;

Hendy, Philip ;

Irving, Peter ;

Johnston, Emma L. ;

Johnston, Matthew ;

Kennedy, Nicholas A. ;

Lal, Simon ;

Lamb, Christopher A. ;

Lees, Charlie W. ;

Lindsay, James O. ;

Lithgo, Karen ;

Lockett, Melanie ;

Maggs, Daniel ;

Mann, Steve ;

Mansfield, John ;

Mason, Joy ;

McCartney, Sara ;

Murray, Charles D. ;

Nowell, Emma ;

Parkes, Miles ;

Russell, Richard K. ;

Satsangi, Jack ;

Singh, Abhey ;

Stansfield, Catherine ;

Thomson, John ;

Warner, Ben ;

Wilson, David C. .

ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2016, 43 (08) :910-923

[10]

Ahmed Waseem, 2016, Gastroenterol Hepatol (N Y), V12, P668

← 1 2 3 4 5 6 7 8 9 10 →