Photoredox-Mediated Net-Neutral Radical/Polar Crossover Reactions

被引：146
作者：
Wiles, Rebecca J. [1 ]
Molander, Gary A. [1 ]
机构：
[1] Univ Penn, Dept Chem, 231 S 34th St, Philadelphia, PA 19104 USA
来源：
ISRAEL JOURNAL OF CHEMISTRY | 2020年 / 60卷 / 3-4期
关键词：
photoredox catalysis; radical polar crossover; catalysis; redox-neutral; radical; VISIBLE-LIGHT PHOTOREDOX; C-H FUNCTIONALIZATION; METAL-FREE; CARBOXYLIC-ACIDS; ALKYL-HALIDES; GENERATION; ARYLATION; CATALYSIS; CONSTRUCTION; HETEROARENES;
D O I：
10.1002/ijch.201900166
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Radical/Polar Crossover (RPC) chemistry is a rapidly growing subset of photoredox catalysis that is characterized by transformations featuring both radical and ionic modes of reactivity. Net-neutral RPC is particularly interesting in that both the single-electron oxidation and reduction steps occur through interaction with the photocatalyst, thus precluding the need for exogenous oxidants or reductants. As such, these transformations facilitate rapid incorporation of molecular complexity while maintaining mild reaction conditions. This review covers recent advances in photoredox-mediated net-neutral RPC synthetic methods, with a particular emphasis on C-C bond-forming reactions.
引用
收藏
页码：281 / 293
页数：13
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