DETECTION OF METHYLMALONIC ACID (MMA) IN PLASMA USING HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY (HILIC) COUPLED WITH MASS SPECTROMETRY (MS) OR TANDEM MASS SPECTROMETRY (MS/MS)

被引：0

作者：

Dube, Maricar

Appelblad, Patrik

机构：

来源：

CHEMICAL & ENGINEERING NEWS | 2015年

关键词：

SERUM;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Methylmalonic acid (MMA) is a biomarker for vitamin B12 deficiency. This application note describes a fast, simple, and sensitive method to detect MMA in plasma that uses a zwitterionic hydrophilic interaction chromatography (ZIC (R)-HILIC) column with LC-MS or LC-MS/MS.

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页码：10 / 11

页数：2

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