DETECTION OF METHYLMALONIC ACID (MMA) IN PLASMA USING HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY (HILIC) COUPLED WITH MASS SPECTROMETRY (MS) OR TANDEM MASS SPECTROMETRY (MS/MS)

被引：0
作者：
Dube, Maricar
Appelblad, Patrik
机构：
来源：
CHEMICAL & ENGINEERING NEWS | 2015年
关键词：
SERUM;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Methylmalonic acid (MMA) is a biomarker for vitamin B12 deficiency. This application note describes a fast, simple, and sensitive method to detect MMA in plasma that uses a zwitterionic hydrophilic interaction chromatography (ZIC (R)-HILIC) column with LC-MS or LC-MS/MS.
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页码：10 / 11
页数：2
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