Microwave assisted synthesis of chiral imidazolyl and pyrazolyl alcohols

被引：40

作者：

Glas, H ^{[1
]}

Thiel, WR ^{[1
]}

机构：

[1] Tech Univ Munich, Inst Anorgan Chem, D-85747 Garching, Germany

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 31期

关键词：

microwave heating; amino alcohols; imidazoles; pyrazoles;

D O I：

10.1016/S0040-4039(98)01114-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Microwave assisted ring opening of (R)-styrene epoxide with pyrazole and imidazole gives the corresponding (R)-configurated (1-phenyl)(2-azolyl)ethanols in high yields. In the case of pyrazole, the application of microwave heating increases both, chemo- and regioselectivity compared to conventional heating methods. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：5509 / 5510

页数：2

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