Obesity as a Thrombogenic and Cardiovascular Risk Factor in Children

被引：0

作者：

Cominato, Louise ^{[1
]}

Franco, Ruth Rocha ^{[1
]}

Ybarra, Marina ^{[1
]}

Frascino, Alexandre Viana ^{[1
]}

Steinmetz, Leandra ^{[1
]}

Ferraro, Alexandre Archanjo ^{[1
]}

Aivazoglou Carneiro, Jorge David ^{[1
]}

Damiani, Durval ^{[1
]}

机构：

[1] Inst Crianca, Sao Paulo, Brazil

来源：

HORMONE RESEARCH IN PAEDIATRICS | 2022年 / 94卷 / 11-12期

关键词：

Childhood obesity; Thrombin generation; Fibrinogen; D-dimer; Body mass index; THROMBIN GENERATION;

D O I：

10.1159/000519264

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background/Aims:Obesity leads to increased risk of thromboembolic events in adults, but few studies have addressed the relationship between obesity and thrombogenic risk during childhood.The aim of this study was to evaluate the prothrombotic state of obese children in comparison with healthy children. Methods: Thrombin generation, fibrinogen, and D-dimer levels, along with metabolic parameters, were measured in 72 prepubertal children, of which 47 were obese and 25 eutrophic. Results: A significant increase in thrombin generation, fibrinogen, and dyslipidemia was found among obese patients. Conclusion: A prothrombotic state develops in childhood obesity during the prepubertal phase. (C) 2021 S. Karger AG, Basel

引用

页码：410 / 415

页数：6

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