MULTICOMPONENT, ONE-POT SYNTHESIS OF HIGHLY SUBSTITUTED PYRIDINES WITH ZINC OXIDE NANOPARTICLES AS CATALYST

被引:0
|
作者
Patil, Kiran [1 ,3 ]
Kumbhar, Deepak [2 ]
Patil, Amol [2 ]
Karhale, Shrikrishna [2 ]
Helavi, Vasant [3 ]
机构
[1] Dr Ghali Coll, Dept Chem, Gadhinglaj, Maharashtra, India
[2] Shivaji Univ, Dept Chem, Kolhapur, Maharashtra, India
[3] Rajaram Coll, Dept Chem, Kolhapur, Maharashtra, India
关键词
ZnO Nanoparticles; Microwave irradiation; Multicomponent reaction; Pyridine derivatives; GREEN SYNTHESIS; ZNO NANOPARTICLES; EFFICIENT; DERIVATIVES; MCR;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
ZnO nanoparticles were used for a highly efficient one-pot synthesis of highly substituted pyridines by the three component condensation reaction of aromatic aldehydes, malononitrile, and ammonium acetate in the mixture of methanol and water as solvent under classical heating. Using microwave heating, reaction times were shortened from 3 hr to 3 min. The advantage of this method includes the use of green catalyst, short reaction time, easy work up, and excellent yields. [GRAPHICS]
引用
收藏
页码:157 / 164
页数:8
相关论文
共 50 条
  • [1] Efficient one-pot synthesis of substituted pyridines through multicomponent reaction
    Xin, Xin
    Wang, Yan
    Kumar, Santosh
    Liu, Xu
    Lin, Yingjie
    Dong, Dewen
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2010, 8 (13) : 3078 - 3082
  • [2] Microwave-assisted, one-pot multicomponent synthesis of highly substituted pyridines using KF/alumina
    Singh, Krishna Nand
    Singh, Satish Kumar
    ARKIVOC, 2009, : 153 - 160
  • [3] Convenient, multicomponent, one-pot synthesis of highly substituted pyridines under solvent-free conditions
    Mobinikhaledi, Akbar
    Asadbegi, Sajad
    Bodaghifard, Mohammad Ali
    SYNTHETIC COMMUNICATIONS, 2016, 46 (19) : 1605 - 1611
  • [4] Organic Catalytic Multicomponent One-Pot Synthesis of Highly Substituted Pyrroles
    Jing, Xiaobi
    Pan, Xin
    Li, Zhen
    Bi, Xiaoxin
    Yan, Chaoguo
    Zhu, Hongxiang
    SYNTHETIC COMMUNICATIONS, 2009, 39 (21) : 3833 - 3844
  • [5] ZnO Nanoparticles as New and Efficient Catalyst for the One-pot Synthesis of Polyfunctionalized Pyridines
    Safaei-Ghomi, Javad
    Ghasemzadeh, Mohammad Ali
    ACTA CHIMICA SLOVENICA, 2012, 59 (03) : 697 - 702
  • [6] L-proline catalyzed an efficient multicomponent one-pot synthesis of poly substituted pyridines
    Janardhan, B.
    Ravibabu, V.
    Crooks, Peter. A.
    Rajitha, B.
    ORGANIC COMMUNICATIONS, 2012, 5 (04) : 186 - 195
  • [7] One-pot multicomponent synthesis of highly substituted piperidines using p-toluenesulfonic acid monohydrate as catalyst
    Sajadikhah, Seyed Sajad
    Maghsoodlou, Malek Taher
    Hazeri, Nourallah
    Habibi-Khorassani, Sayyed Mostafa
    Shams-Najafi, Sayyed Jalal
    MONATSHEFTE FUR CHEMIE, 2012, 143 (06): : 939 - 945
  • [8] One-pot multicomponent synthesis of highly substituted piperidines using p-toluenesulfonic acid monohydrate as catalyst
    Seyed Sajad Sajadikhah
    Malek Taher Maghsoodlou
    Nourallah Hazeri
    Sayyed Mostafa Habibi-Khorassani
    Sayyed Jalal Shams-Najafi
    Monatshefte für Chemie - Chemical Monthly, 2012, 143 : 939 - 945
  • [9] One-pot multicomponent synthesis of highly substituted bicyclo[2.2.2]octane derivatives using bismuth nitrate as a catalyst
    Gein, Vladimir L.
    Yankin, Andrei N.
    Nosova, Natalia V.
    Dmitriev, Maxim V.
    Slepukhin, Pavel A.
    TETRAHEDRON LETTERS, 2016, 57 (22) : 2441 - 2444
  • [10] Tin oxide nanoparticles (SnO2-NPs): An efficient catalyst for the one-pot synthesis of highly substituted imidazole derivatives
    Fallah, Nasibeh Shahrivar
    Mokhtary, Masoud
    JOURNAL OF TAIBAH UNIVERSITY FOR SCIENCE, 2015, 9 (04): : 531 - 537