Rapid Drug Susceptibility Testing with a Molecular Beacon Assay Is Associated with Earlier Diagnosis and Treatment of Multidrug-Resistant Tuberculosis in California

被引:17
作者
Banerjee, Ritu [1 ]
Allen, Jennifer [2 ]
Lin, S. -Y. Grace [3 ]
Westenhouse, Janice [2 ]
Desmond, Ed [3 ]
Schecter, Gisela F. [2 ]
Scott, Cheryl [2 ]
Raftery, Ann [4 ]
Mase, Sundari [5 ]
Watt, James P. [2 ]
Flood, Jennifer [2 ]
机构
[1] Mayo Clin, Div Pediat Infect Dis, Rochester, MN 55905 USA
[2] Calif Dept Publ Hlth, TB Control Branch, Div Communicable Dis, Ctr Infect Dis, Richmond, CA USA
[3] Calif Dept Publ Hlth, Microbial Dis Lab, Div Communicable Dis, Ctr Infect Dis, Richmond, CA USA
[4] Francis J Curry Natl TB Ctr, San Francisco, CA USA
[5] Ctr Dis Control & Prevent, Div TB Eliminat, Atlanta, GA USA
关键词
MYCOBACTERIUM-TUBERCULOSIS; MUTATIONS;
D O I
10.1128/JCM.01236-10
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
To assess the clinical impact of a molecular beacon (MB) assay that detects multidrug-resistant tuberculosis (MDR TB), we retrospectively reviewed records of 127 MDR TB patients with and without MB testing between 2004 and 2007. Use of the MB assay reduced the time to detection and treatment of MDR TB.
引用
收藏
页码:3779 / 3781
页数:3
相关论文
共 10 条
[1]  
[Anonymous], 2008, MOL LINE PROBE ASSAY
[2]  
Centers for Disease Control and Prevention, 2009, REP EXP CONS RAP MOL
[3]   Evaluation of a line probe assay kit for characterization of rpoB mutations in rifampin-resistant Mycobacterium tuberculosis isolates from new York City [J].
Cooksey, RC ;
Morlock, GP ;
Glickman, S ;
Crawford, JT .
JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (05) :1281-1283
[4]   Delay in diagnosis among hospitalized patients with active tuberculosis-predictors and outcomes [J].
Greenaway, C ;
Menzies, D ;
Fanning, A ;
Grewal, R ;
Yuan, L ;
FitzGerald, JM .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 165 (07) :927-933
[5]   Rapid detection of isoniazid and rifampin resistance mutations in Mycobacterium tuberculosis complex from cultures or smear-positive sputa by use of molecular beacons [J].
Lin, SYG ;
Probert, W ;
Lo, M ;
Desmond, E .
JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (09) :4204-4208
[6]  
Phoa LL, 2005, RESPIROLOGY, V10, P196
[7]   Molecular beacon sequence analysis for detecting drug resistance in Mycobacterium tuberculosis [J].
Piatek, AS ;
Tyagi, S ;
Pol, AC ;
Telenti, A ;
Miller, LP ;
Kramer, FR ;
Alland, D .
NATURE BIOTECHNOLOGY, 1998, 16 (04) :359-363
[8]   Increasing Proportions of Advanced Pulmonary Tuberculosis Reported in the United States Are Delays in Diagnosis on the Rise? [J].
Wallace, Ryan MacLaren ;
Kammerer, J. Steve ;
Iademarco, Michael F. ;
Althomsons, Sandy P. ;
Winston, Carla A. ;
Navin, Thomas R. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 180 (10) :1016-1022
[9]  
World Health Organization (WHO), 2006, WHOHTMTB2006361
[10]  
Wright A., 2006, Morbidity and Mortality Weekly Report, V55, P301