ACQUIRED HEMOPHILIA A

被引：20

作者：

Franchini, Massimo ^{[1
]}

Lippi, Giuseppe ^{[2
]}

机构：

[1] Univ Hosp Parma, Dept Pathol & Lab Med, Immunohematol & Transfus Ctr, Parma, Italy

[2] Univ Hosp Parma, Clin Chem Lab, Dept Pathol & Lab Med, Parma, Italy

来源：

ADVANCES IN CLINICAL CHEMISTRY, VOL 54 | 2011年 / 54卷

关键词：

FACTOR-VIII; ANTIBODIES; RITUXIMAB; INACTIVATION; INHIBITORS; PROGNOSIS; DIAGNOSIS; KINETICS; BINDING; IGG;

D O I：

10.1016/B978-0-12-387025-4.00003-0

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Acquired hemophilia A is a rare but often life-threatening hemorrhagic disorder characterized by an autoantibody directed against coagulation factor VIII. Fifty per cent of cases are idiopathic whereas the remaining 50% are associated with pregnancy, autoimmune conditions, malignancies and drugs. In this review the actual knowledge on diagnostic and therapeutic aspects of this disease will be summarized.

引用

页码：71 / 80

页数：10

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