Osteoporosis

被引:33
作者
Brown, SA
Rosen, CJ
机构
[1] St Joseph Hosp, Maine Ctr Osteoporosis Res & Educ, Bangor, ME 04401 USA
[2] Univ N Carolina, Dept Med, Div Endocrinol, Chapel Hill, NC 27599 USA
[3] Jackson Lab, Bar Harbor, ME 04609 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S0025-7125(03)00065-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Osteoporosis has a tremendous impact on the lives of many postmenopausal women. It is encouraging that effective treatments for this disease abound and the challenge is to ensure that those most in need of diagnosis or therapy obtain adequate care. Further research is expected to clarify the role of combination therapy or sequential use of different agents for the maximum benefit in fracture protection. There is an array of efficacious options to consider when diagnosing and treating osteoporosis so that patients and their caregivers can remain optimistic about the management of this chronic disease and prevention of future fractures.
引用
收藏
页码:1039 / +
页数:26
相关论文
共 115 条
[11]  
Bhudhikanok GS, 1996, J BONE MINER RES, V11, P1545
[12]   Prevalent vertebral deformities predict hip fractures and new vertebral deformities but not wrist fractures [J].
Black, DM ;
Arden, NK ;
Palermo, L ;
Pearson, J ;
Cummings, SR .
JOURNAL OF BONE AND MINERAL RESEARCH, 1999, 14 (05) :821-828
[13]   Fracture risk reduction with alendronate in women with osteoporosis: The Fracture Intervention Trial [J].
Black, DM ;
Thompson, DE ;
Bauer, DC ;
Ensrud, K ;
Musliner, T ;
Hochberg, MC ;
Nevitt, MC ;
Suryawanshi, S ;
Cummings, SR .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2000, 85 (11) :4118-4124
[14]   Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures [J].
Black, DM ;
Cummings, SR ;
Karpf, DB ;
Cauley, JA ;
Thompson, DE ;
Nevitt, MC ;
Bauer, DC ;
Genant, HK ;
Haskell, WL ;
Marcus, R ;
Ott, SM ;
Torner, JC ;
Quandt, SA ;
Reiss, TF ;
Ensrud, KE .
LANCET, 1996, 348 (9041) :1535-1541
[15]   A Randomized double-blind trial to compare the efficacy of teriparatide [recombinant human parathyroid hormone (1-34)] with alendronate in postmenopausal women with osteoporosis [J].
Body, JJ ;
Gaich, GA ;
Scheele, WH ;
Kulkarni, PM ;
Miller, PD ;
Peretz, A ;
Dore, RK ;
Correa-Rotter, R ;
Papaioannou, A ;
Cumming, DC ;
Hodsman, AB .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2002, 87 (10) :4528-4535
[16]   Alendronate and estrogen effects in postmenopausal women with low bone mineral density [J].
Bone, HG ;
Greenspan, SL ;
McKeever, C ;
Bell, N ;
Davidson, M ;
Downs, RW ;
Emkey, R ;
Meunier, PJ ;
Miller, SS ;
Mulloy, AL ;
Recker, RR ;
Weiss, SR ;
Heyden, N ;
Musliner, T ;
Suryawanshi, S ;
Yates, AJ ;
Lombardi, A .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2000, 85 (02) :720-726
[17]  
Booth SL, 2000, AM J CLIN NUTR, V71, P1201
[18]   Prediction of the strength of the elderly proximal femur by bone mineral density and quantitative ultrasound measurements of the heel and tibia [J].
Bouxsein, ML ;
Coan, BS ;
Lee, SC .
BONE, 1999, 25 (01) :49-54
[19]   High bone density due to a mutation in LDL-receptor-related protein 5 [J].
Boyden, LM ;
Mao, JH ;
Belsky, J ;
Mitzner, L ;
Farhi, A ;
Mitnick, MA ;
Wu, DQ ;
Insogna, K ;
Lifton, RP .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (20) :1513-1521
[20]   Effects of hormone therapy on bone mineral density - Results from the postmenopausal estrogen/progestin interventions (PEPI) trial [J].
Bush, TL ;
Wells, HB ;
James, MK ;
BarrettConnor, E ;
Marcus, R ;
Greendale, G ;
Hunsberger, S ;
McGowan, J .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1996, 276 (17) :1389-1396