New insights into site-specific variations in RA and OA

被引：1

作者：

Ospelt, Caroline ^{[1
]}

Frank-Bertoncelj, Mojca ^{[1
]}

机构：

[1] Univ Zurich Hosp, Dept Rheumatol, Ctr Expt Rheumatol, Wagistr 14, CH-8952 Zurich, Switzerland

来源：

NATURE REVIEWS RHEUMATOLOGY | 2016年 / 12卷 / 09期

关键词：

RHEUMATOID-ARTHRITIS; SYNOVIAL FIBROBLASTS; METHYLOME SIGNATURE; SUSCEPTIBILITY; OSTEOARTHRITIS; TRANSCRIPTOME; METHYLATION; EXPRESSION; KNEE; GDF5;

D O I：

10.1038/nrrheum.2016.133

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Fibroblast-like synoviocytes isolated from the knee and hip joints of patients with rheumatoid arthritis or osteoarthritis have now been shown to have site-specific DNA methylation signatures. Although preliminary, the data point towards a new view of joint involvement in arthritis.

引用

页码：P505 / +

页数：2

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