New insights into site-specific variations in RA and OA

被引：1
|
作者：
Ospelt, Caroline [1 ]
Frank-Bertoncelj, Mojca [1 ]
机构：
[1] Univ Zurich Hosp, Dept Rheumatol, Ctr Expt Rheumatol, Wagistr 14, CH-8952 Zurich, Switzerland
来源：
NATURE REVIEWS RHEUMATOLOGY | 2016年 / 12卷 / 09期
关键词：
RHEUMATOID-ARTHRITIS; SYNOVIAL FIBROBLASTS; METHYLOME SIGNATURE; SUSCEPTIBILITY; OSTEOARTHRITIS; TRANSCRIPTOME; METHYLATION; EXPRESSION; KNEE; GDF5;
D O I：
10.1038/nrrheum.2016.133
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Fibroblast-like synoviocytes isolated from the knee and hip joints of patients with rheumatoid arthritis or osteoarthritis have now been shown to have site-specific DNA methylation signatures. Although preliminary, the data point towards a new view of joint involvement in arthritis.
引用
收藏
页码：P505 / +
页数：2
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