Infliximab therapy for Crohn's disease in the presence of chronic hepatitis C infection

被引：63
作者：
Campbell, S [1 ]
Ghosh, S [1 ]
机构：
[1] Western Gen Hosp, Gastrointestinal Unit, Dept Med Sci, Edinburgh EH4 2XU, Midlothian, Scotland
来源：
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | 2001年 / 13卷 / 02期
关键词：
Crohn's disease; hepatitis C; infliximab; tumour necrosis factor alpha;
D O I：
10.1097/00042737-200102000-00016
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Treatment of Crohn's disease with infliximab is an important drug therapy for patients with refractory and fistulating disease. There are concerns over its use in a proportion of Crohn's patients with concurrent hepatitis C infection, since there are theoretical risks of accelerated hepatic decompensation due to the immunomodulatory impact of infliximab. We report a patient with both Crohn's disease and ongoing active hepatitis C infection who underwent infliximab therapy, with no worsening of his liver function or PCR status. Eur J Gastroenterol Hepatol 13:191-192 (C) 2001 Lippincott Williams & Wilkins.
引用
收藏
页码：191 / 192
页数：2
相关论文
共 50 条
  • [41] Demyelination-like syndrome in Crohn's disease after infliximab therapy
    Freeman, HJ
    Flak, B
    CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2005, 19 (05): : 313 - 316
  • [42] Neurological symptoms suggestive of demyelination in Crohn's disease after infliximab therapy
    Dubcenco, Elena
    Ottaway, Clifford A.
    Chen, Dean L.
    Baker, Jeffrey P.
    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2006, 18 (05) : 565 - 566
  • [43] Chronic hepatitis C and Crohn's disease:: Nosocomial infection treatment with PEG-interferon plus ribavirin
    Salcedo-Mora, Xamila
    Mate, Jose
    Medina, Jesus
    Chab, Syong J. Nam
    Gisbert, Javier P.
    Moreno-Otero, Ricardo
    DIGESTION, 2006, 73 (04) : 210 - 214
  • [44] Large Bowel Progressive Stricture after Infliximab Therapy for Crohn's Disease
    Matsueda, Katsunori
    Toyokawa, Tatsuya
    Sakata, Masahiro
    Fujita, Isao
    Horii, Jouichiro
    INTERNAL MEDICINE, 2018, 57 (15) : 2179 - 2183
  • [45] Colon Cancer After Infliximab Therapy for Crohn’s Disease
    Frederico Ferreira
    Susana Lopes
    Guilherme Macedo
    BioDrugs, 2010, 24 : 18 - 21
  • [46] Guidelines for treatment with infliximab for Crohn's disease
    Hommes, D. W.
    Oldenburg, B.
    van Bodegraven, A. A.
    van Hogezand, R. A.
    de Jong, D. J.
    Romberg-Camps, M. J. L.
    van der Woude, J.
    Dijkstra, G.
    NETHERLANDS JOURNAL OF MEDICINE, 2006, 64 (07) : 219 - 229
  • [47] Infliximab to treat Crohn's disease: an update
    Cottone, M.
    Criscuoli, V.
    CLINICAL AND EXPERIMENTAL GASTROENTEROLOGY, 2011, 4 : 227 - 238
  • [48] Desensitisation to infliximab in patients with Crohn's disease
    Lelong, J
    Duburque, C
    Fournier, C
    Colombel, JF
    Desreumaux, P
    Tonnel, AB
    Wallaert, B
    REVUE DES MALADIES RESPIRATOIRES, 2005, 22 (02) : 239 - 246
  • [49] Infliximab dose intensification in Crohn's disease
    Regueiro, Miguel
    Siemanowski, Benjamin
    Kip, Kevin E.
    Plevy, Scott
    INFLAMMATORY BOWEL DISEASES, 2007, 13 (09) : 1093 - 1099
  • [50] Fecal Calprotectin Pretreatment and Induction Infliximab Levels for Prediction of Primary Nonresponse to Infliximab Therapy in Crohn's Disease
    Beltran, Belen
    Iborra, Marisa
    Saez-Gonzalez, Esteban
    Marques-Minana, Maria R.
    Moret, Ines
    Cerrillo, Elena
    Tortosa, Luis
    Bastida, Guillermo
    Hinojosa, Joaquin
    Luis Poveda-Andres, Jose
    Nos, Pilar
    DIGESTIVE DISEASES, 2019, 37 (02) : 108 - 115
12345