Infliximab therapy for Crohn's disease in the presence of chronic hepatitis C infection

被引：63
作者：
Campbell, S [1 ]
Ghosh, S [1 ]
机构：
[1] Western Gen Hosp, Gastrointestinal Unit, Dept Med Sci, Edinburgh EH4 2XU, Midlothian, Scotland
来源：
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | 2001年 / 13卷 / 02期
关键词：
Crohn's disease; hepatitis C; infliximab; tumour necrosis factor alpha;
D O I：
10.1097/00042737-200102000-00016
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Treatment of Crohn's disease with infliximab is an important drug therapy for patients with refractory and fistulating disease. There are concerns over its use in a proportion of Crohn's patients with concurrent hepatitis C infection, since there are theoretical risks of accelerated hepatic decompensation due to the immunomodulatory impact of infliximab. We report a patient with both Crohn's disease and ongoing active hepatitis C infection who underwent infliximab therapy, with no worsening of his liver function or PCR status. Eur J Gastroenterol Hepatol 13:191-192 (C) 2001 Lippincott Williams & Wilkins.
引用
收藏
页码：191 / 192
页数：2
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