Myeloid derived dendritic cells inhibit CD8+ T cell responses by down modulating NkG2D and 4-1BB expression

被引：0
作者：
Kim, Young-June [1 ,2 ]
Broxmeyer, Hal E. [1 ,2 ]
机构：
[1] Indiana Univ, Sch Med, Bloomington, IN 47405 USA
[2] Walther Oncol Ctr, Walther Canc Inst, Indianapolis, IN USA
来源：
BLOOD | 2007年 / 110卷 / 11期
关键词：
D O I：
10.1182/blood.V110.11.315.315
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
315
引用
收藏
页码：99A / 100A
页数：2
相关论文
共 50 条
  • [21] A critical role for 4-1BB in allograft rejection mediated by CD8+ T cells
    Kim, OS
    Guo, Z
    Wang, J
    Hart, J
    Larsen, CP
    Newell, KA
    LABORATORY INVESTIGATION, 2003, 83 (01) : 124A - 124A
  • [22] Decreased NKG2D expression on CD8+ T cell is involved in immune evasion in patients with gastric cancer
    Osaki, Tomohiro
    Saito, Hiroaki
    Yoshikawa, Toshiaki
    Matsumoto, Sachiko
    Tatebe, Shigeru
    Tsujitani, Shunichi
    Ikeguchi, Masahide
    CLINICAL CANCER RESEARCH, 2007, 13 (02) : 382 - 387
  • [23] NK cells suppress CD8+ T cell immunity via NKG2D in severe aplastic anemia
    Chen, Tong
    Zhang, Tian
    Liu, Chunyan
    Wang, ChaoMeng
    Ding, Shaoxue
    Shao, ZongHong
    Fu, Rong
    CELLULAR IMMUNOLOGY, 2019, 335 : 6 - 14
  • [24] NKG2D optimizes CD8+ T cell function while certifying them to become memory cells
    Perez, Cynthia
    Prajapati, Kushal
    Burke, Brianna
    Plaza-Rojas, Lourdes
    Guevara-Patino, Jose A.
    JOURNAL OF IMMUNOLOGY, 2016, 196
  • [25] Expression and function of 4-1BB during CD4 versus CD8 T cell responses in vivo
    Dawicki, W
    Watts, TH
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2004, 34 (03) : 743 - 751
  • [26] Cutting edge:: NKG2D is a costimulatory receptor for human naive CD8+ T cells
    Maasho, K
    Opoku-Anane, J
    Marusina, AI
    Coligan, JE
    Borrego, F
    JOURNAL OF IMMUNOLOGY, 2005, 174 (08) : 4480 - 4484
  • [27] Therapeutic potential of 4-1BB (CD137) as a regulator for effector CD8+ T cells
    Kim, YJ
    Broxmeyer, HE
    JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH, 2001, 10 (04): : 441 - 449
  • [28] IL-21 down-regulates NKG2D expression and function in human NK cells and differentially regulates NKG2D and CD28 expression on CD8+T cells
    Burgess, Steven James
    Marusina, Alina
    Borrego, Francisco
    Coligan, John
    JOURNAL OF IMMUNOLOGY, 2006, 176 : S27 - S27
  • [29] Systemic NKG2D down-regulation impairs NK and CD8 T cell responses in vivo
    Wiemann, K
    Mittrücker, HW
    Feger, U
    Welte, SA
    Yokoyama, WM
    Spies, T
    Rammensee, HG
    Steinle, A
    JOURNAL OF IMMUNOLOGY, 2005, 175 (02) : 720 - 729
  • [30] Role of 4-1BB/4-1BBL in CD8 T cell responses
    Watts, T
    Srokowski, C
    Pulle, G
    Snell, L
    Bertram, E
    IMMUNOLOGY, 2005, 116 : 6 - 6
12345