NIR-II Organic Nanotheranostics for Precision Oncotherapy

被引：99
作者：
Dai, Hanming [1 ,2 ]
Wang, Xiaorui [1 ,2 ]
Shao, Jinjun [1 ,2 ]
Wang, Wenjun [3 ]
Mou, Xiaozhou [4 ]
Dong, Xiaochen [1 ,2 ]
机构：
[1] Nanjing Tech Univ NanjingTech, Key Lab Flexible Elect KLOFE, Nanjing 211816, Peoples R China
[2] Nanjing Tech Univ NanjingTech, Inst Adv Mat IAM, Nanjing 211816, Peoples R China
[3] Liaocheng Univ, Sch Phys Sci & Informat Technol, Liaocheng 252059, Shandong, Peoples R China
[4] Zhejiang Prov Peoples Hosp, Hangzhou Med Coll, Affiliated Peoples Hosp, Clin Res Inst, Hangzhou 310014, Peoples R China
来源：
SMALL | 2021年 / 17卷 / 44期
关键词：
organic nanotheranostics; precision oncotherapy; second near-infrared; SEMICONDUCTING POLYMER NANOPARTICLES; INTRAMOLECULAR CHARGE-TRANSFER; NEAR-INFRARED WINDOW; PHOTOTHERMAL THERAPY; CONJUGATED POLYMER; RATIONAL DESIGN; RECENT PROGRESS; GAS THERAPY; FLUORESCENCE; CANCER;
D O I：
10.1002/smll.202102646
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Precision oncotherapy can remove tumors without causing any apparent iatrogenic damage or irreversible side effects to normal tissues. Second near-infrared (NIR-II) nanotheranostics can simultaneously perform diagnostic and therapeutic modalities in a single nanoplatform, which exhibits prominent perspectives in tumor precision treatment. Among all NIR-II nanotheranostics, NIR-II organic nanotheranostics have shown an exceptional promise for translation in clinical tumor treatment than NIR-II inorganic nanotheranostics in virtue of their good biocompatibility, excellent reproducibility, desirable excretion, and high biosafety. In this review, recent progress of NIR-II organic nanotheranostics with the integration of tumor diagnosis and therapy is systematically summarized, focusing on the theranostic modes and performances. Furthermore, the current status quo, problems, and challenges are discussed, aiming to provide a certain guiding significance for the future development of NIR-II organic nanotheranostics for precision oncotherapy.
引用
收藏
页数：23
相关论文
共 156 条
[1]   Single-Molecular Near-Infrared-II Theranostic Systems: Ultrastable Aggregation-Induced Emission Nanoparticles for Long-Term Tracing and Efficient Photothermal Therapy [J].
Alifu, Nuernisha ;
Zebibula, Abudureheman ;
Qi, Ji ;
Zhang, Hequn ;
Sun, Chaowei ;
Yu, Xiaoming ;
Xue, Dingwei ;
Lam, Jacky W. Y. ;
Li, Gonghui ;
Qian, Jun ;
Tang, Ben Zhong .
ACS NANO, 2018, 12 (11) :11282-11293
[2]   A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging [J].
Antaris, Alexander L. ;
Chen, Hao ;
Diao, Shuo ;
Ma, Zhuoran ;
Zhang, Zhe ;
Zhu, Shoujun ;
Wang, Joy ;
Lozano, Alexander X. ;
Fan, Quli ;
Chew, Leila ;
Zhu, Mark ;
Cheng, Kai ;
Hong, Xuechuan ;
Dai, Hongjie ;
Cheng, Zhen .
NATURE COMMUNICATIONS, 2017, 8
[3]  
Antaris AL, 2016, NAT MATER, V15, P235, DOI [10.1038/NMAT4476, 10.1038/nmat4476]
[4]   Novel aza-BODIPY based small molecular NIR-II fluorophores for in vivo imaging [J].
Bai, Lei ;
Sun, Pengfei ;
Liu, Yi ;
Zhang, Hang ;
Hu, Wenbo ;
Zhang, Wansu ;
Liu, Zhipeng ;
Fan, Quli ;
Li, Lin ;
Huang, Wei .
CHEMICAL COMMUNICATIONS, 2019, 55 (73) :10920-10923
[5]   Cervical cancer in Ethiopia - predictors of advanced stage and prolonged time to diagnosis [J].
Begoihn, Matthias ;
Mathewos, Assefa ;
Aynalem, Abreha ;
Wondemagegnehu, Tigeneh ;
Moelle, Ulrike ;
Gizaw, Muluken ;
Wienke, Andreas ;
Thomssen, Christoph ;
Worku, Dawit ;
Addissie, Adamu ;
Jemal, Ahmedin ;
Kantelhardt, Eva Johanna .
INFECTIOUS AGENTS AND CANCER, 2019, 14 (01)
[6]   Cellulose nanocomposites: Fabrication and biomedical applications [J].
Joseph B. ;
Sagarika V.K. ;
Sabu C. ;
Kalarikkal N. ;
Thomas S. .
Journal of Bioresources and Bioproducts, 2020, 5 (04) :223-237
[7]   Fused-Ring Small-Molecule-Based Bathochromic Nano-agents for Tumor NIR-II Fluorescence Imaging-Guided Photothermal/Photodynamic Therapy [J].
Cai, Yu ;
Tang, Chuanchao ;
Wei, Zheng ;
Song, Chuanhui ;
Zou, Huihui ;
Zhang, Guorong ;
Ran, Jianchuan ;
Han, Wei .
ACS APPLIED BIO MATERIALS, 2021, 4 (02) :1942-1949
[8]   Optical nano-agents in the second near-infrared window for biomedical applications [J].
Cai, Yu ;
Wei, Zheng ;
Song, Chuanhui ;
Tang, Chuanchao ;
Han, Wei ;
Dong, Xiaochen .
CHEMICAL SOCIETY REVIEWS, 2019, 48 (01) :22-37
[9]   Organic Dye Based Nanoparticles for Cancer Phototheranostics [J].
Cai, Yu ;
Si, Weili ;
Huang, Wei ;
Chen, Peng ;
Shao, Jinjun ;
Dong, Xiaochen .
SMALL, 2018, 14 (25)
[10]   Semiconducting polymer-based nanoparticles with strong absorbance in NIR-II window for in vivo photothermal therapy and photoacoustic imaging [J].
Cao, Ziyang ;
Feng, Liangzhu ;
Zhang, Guobing ;
Wang, Junxia ;
Shen, Song ;
Li, Dongdong ;
Yang, Xianzhu .
BIOMATERIALS, 2018, 155 :103-111
12345678910