Cerebellar Transcranial Direct Current Stimulation in Children with Developmental Coordination Disorder: A Randomized, Double-Blind, Sham-Controlled Pilot Study

被引:1
作者
Akremi, Haifa [1 ]
Hamel, Raphael [2 ,3 ]
Dumas, Anne [2 ,3 ]
Camden, Chantal [1 ,3 ]
Corriveau, Helene [1 ,3 ]
Lepage, Jean-Francois [2 ,3 ,4 ]
机构
[1] Sherbrooke Univ, Sch Rehabil, 3001-12th Ave North, Sherbrooke, PQ, Canada
[2] Sherbrooke Univ, Dept Pediat, 3001-12th Ave North, Sherbrooke, PQ, Canada
[3] Sherbrooke Univ, Res Ctr, 3001-12th Ave North, Sherbrooke, PQ, Canada
[4] Sherbrooke Univ, Fac Med & Hlth Sci, Dept Pediat, 3001-12th Ave North, Sherbrooke, PQ J1H 5N4, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
Neurostimulation; Neurodevelopmental disorders; Motor learning; Cerebellum; Transcranial direct current stimulation (tDCS); MOTOR CORTEX; PERFORMANCE; TDCS; EXCITABILITY; RELIABILITY; ATTENTION; IMPLICIT;
D O I
10.1007/s10803-021-05202-6
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
Evidence-based therapeutic options for children with developmental coordination disorder (DCD) are scarce. This work explored the effects of cerebellar anodal transcranial direct current stimulation (atDCS) on three 48 h-apart motor sequence learning and upper limb coordination sessions in children with DCD. The results revealed that, as compared to a Sham intervention (n = 10), cerebellar atDCS (n = 10) did not meaningfully improve execution speed but tended to reduce the number of execution errors during motor sequence learning. However, cerebellar atDCS did neither meaningfully influence offline learning nor upper limb coordination, suggesting that atDCS' effects are circumscribed to its application duration. These results suggest that cerebellar atDCS could have beneficial effects as a complementary therapeutic tool for children with DCD.
引用
收藏
页码:3202 / 3213
页数:12
相关论文
共 67 条
  • [1] American Psychiatric Association, 2000, DIAGN STAT MAN MENT, DOI 10.1176/dsm10.1176/appi.books.9780890420249.dsm-iv-tr
  • [2] Effects of cerebellar transcranial direct current stimulation on the cognitive stage of sequence learning
    Ballard, Hannah K.
    Goen, James R. M.
    Maldonado, Ted
    Bernard, Jessica A.
    [J]. JOURNAL OF NEUROPHYSIOLOGY, 2019, 122 (02) : 490 - 499
  • [3] Molecular Mechanisms of Early and Late LTP
    Baltaci, Saltuk Bugra
    Mogulkoc, Rasim
    Baltaci, Abdulkerim Kasim
    [J]. NEUROCHEMICAL RESEARCH, 2019, 44 (02) : 281 - 296
  • [4] CONTROLLING THE FALSE DISCOVERY RATE - A PRACTICAL AND POWERFUL APPROACH TO MULTIPLE TESTING
    BENJAMINI, Y
    HOCHBERG, Y
    [J]. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY, 1995, 57 (01) : 289 - 300
  • [5] Non-Invasive Cerebellar Stimulation in Neurodegenerative Ataxia: A Literature Review
    Benussi, Alberto
    Pascual-Leone, Alvaro
    Borroni, Barbara
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (06)
  • [6] Long term clinical and neurophysiological effects of cerebellar transcranial direct current stimulation in patients with neurodegenerative ataxia
    Benussi, Alberto
    Dell'Era, Valentina
    Cotelli, Maria Sofia
    Turla, Marinella
    Casali, Carlo
    Padovani, Alessandro
    Borroni, Barbara
    [J]. BRAIN STIMULATION, 2017, 10 (02) : 242 - 250
  • [7] Safety of Transcranial Direct Current Stimulation: Evidence Based Update 2016
    Bikson, Marom
    Grossman, Pnina
    Thomas, Chris
    Zannou, Adantchede Louis
    Jiang, Jimmy
    Adnan, Tatheer
    Mourdoukoutas, Antonios P.
    Kronberg, Greg
    Truong, Dennis
    Boggio, Paulo
    Brunoni, Andre R.
    Charvet, Leigh
    Fregni, Felipe
    Fritsch, Brita
    Gillick, Bernadette
    Hamilton, Roy H.
    Hampstead, Benjamin M.
    Jankord, Ryan
    Kirton, Adam
    Knotkova, Helena
    Liebetanz, David
    Liu, Anli
    Loo, Colleen
    Nitsche, Michael A.
    Reis, Janine
    Richardson, Jessica D.
    Rotenberg, Alexander
    Turkeltaub, Peter E.
    Woods, Adam J.
    [J]. BRAIN STIMULATION, 2016, 9 (05) : 641 - 661
  • [8] Biotteau M., 2016, Curr. Dev. Disord. Rep., V3, P152, DOI DOI 10.1007/S40474-016-0084-8
  • [9] Brown-Lum M., 2015, Current Development Disorder Report, V2, P131, DOI [10.1007/s40474-015-0046-6, DOI 10.1007/S40474-015-0046-6]
  • [10] Effects of tDCS on motor learning and memory formation: A consensus and critical position paper
    Buch, Ethan R.
    Santarnecchi, Emiliano
    Antal, Andrea
    Born, Jan
    Celnik, Pablo A.
    Classen, Joseph
    Gerloff, Christian
    Hallett, Mark
    Hummel, Friedhelm C.
    Nitsche, Michael A.
    Pascual-Leone, Alvaro
    Paulus, Walter J.
    Reis, Janine
    Robertson, Edwin M.
    Rothwell, John C.
    Sandrini, Marco
    Schambra, Heidi M.
    Wassermann, Eric M.
    Ziemann, Ulf
    Cohen, Leonardo G.
    [J]. CLINICAL NEUROPHYSIOLOGY, 2017, 128 (04) : 589 - 603