Gut microbes and health

被引：77

作者：

Alvarez, Julia ^{[1
,2
]}

Fernandez Real, Jose Manuel ^{[3
,4
]}

Guarner, Francisco ^{[5
]}

Gueimonde, Miguel ^{[6
]}

Miguel Rodriguez, Juan ^{[7
]}

Saenz de Pipaon, Miguel ^{[8
,9
]}

Sanz, Yolanda ^{[10
]}

机构：

[1] Hosp Univ Principe Asturias, Serv Endocrinol & Nutr, Madrid, Spain

[2] Univ Alcala, Dept Ciencias Salud, Madrid, Spain

[3] Univ Girona, Hosp Univ Dr Josep Trueta, Unitat Diabet Endocrinol & Nutr, Girona, Spain

[4] CIBERobn Fisiopatol Obesidad & Nutr, Madrid, Spain

[5] Vall dHebron Inst Recerca, Unidad Invest Aparato Digest, Barcelona, Spain

[6] IPLA CSIC, Dept Microbiol & Bioquim Prod Lacteos, Villaviciosa, Asturias, Spain

[7] Univ Complutense Madrid, Dept Nutr & Ciencia Alimentos, Madrid, Spain

[8] Hosp Univ La Paz, Serv Neonatol, Madrid, Spain

[9] Univ Autonoma Madrid, Dept Pediat, Madrid, Spain

[10] Consejo Super Invest Cient IATA CSIC, Ecol Microbiana Nutr & Salud, Inst Agroquim & Tecnol Alimentos, Valencia, Spain

来源：

GASTROENTEROLOGIA Y HEPATOLOGIA | 2021年 / 44卷 / 07期

关键词：

Dysbiosis; Eubiosis; Symbiosis; Chronic non-communicable diseases; Industrialisation; Antibiotics; Diet; Probiotics; INTERNATIONAL SCIENTIFIC ASSOCIATION; INTESTINAL MICROBIOTA; CONSENSUS STATEMENT; INSULIN-RESISTANCE; FECAL MICROBIOTA; IRON OVERLOAD; OBESITY; DIET; METABOLISM; PROBIOTICS;

D O I：

10.1016/j.gastrohep.2021.01.009

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The human body is populated by myriads of microorganisms throughout its surface and in the cavities connected to the outside. The microbial colonisers of the intestine (microbiota) are a functional and non-expendable part of the human organism: they provide genes (microbiome) and additional functions to the resources of our species and participate in multiple physiological processes (somatic development, nutrition, immunity, etc.). Some chronic non-communicable diseases of developed society (atopias, metabolic syndrome, inflammatory diseases, cancer and some behaviour disorders) are associated with dysbiosis: loss of species richness in the intestinal microbiota and deviation from the ancestral microbial environment. Changes in the vertical transmission of the microbiome, the use of antiseptics and antibiotics, and dietary habits in industrialised society appear to be at the origin of dysbiosis. Generating and maintaining diversity in the microbiota is a new clinical target for health promotion and disease prevention. (C) 2021 The Author(s). Published by Elsevier Espana, S.L.U.

引用

页码：519 / 535

页数：17

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