Stated preferences for relapsed or refractory mantle cell lymphoma treatments in Sweden and Germany

被引:7
作者
Eriksson, Jennifer [1 ]
Landfeldt, Erik [1 ,2 ]
Ireland, Steve [3 ]
Jackson, Claire [4 ]
Wyatt, Emma [4 ]
Gaudig, Maren [5 ]
机构
[1] ICON Plc, Stockholm, Sweden
[2] Karolinska Inst, Dept Womens & Childrens Hlth, Stockholm, Sweden
[3] Janssen EMEA Business Intelligence, High Wycombe, Bucks, England
[4] Adelphi Res UK, Bollington, England
[5] Janssen Hlth Econ & Market Access EMEA, Neuss, Germany
关键词
discrete choice experiment; interview; overall survival; progression-free survival; treatment administration; treatment preference; DISCRETE-CHOICE EXPERIMENTS; METASTATIC BREAST-CANCER; PATIENT PREFERENCES; CONJOINT-ANALYSIS; TREATMENT DECISIONS; THERAPY; GUIDELINES; PHYSICIANS; OPTIONS; WOMEN;
D O I
10.2217/fon-2020-0018
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: We aimed to elicit treatment preferences in relapsed/refractory mantle cell lymphoma (r/r MCL). Materials & methods: A discrete-choice experiment comprising six attributes ('overall survival', 'progression-free survival', 'fatigue', 'nausea', 'risk of serious infections' and 'treatment administration') was administered to r/r MCL patients, physicians and the general population (GP) in Sweden and Germany. Results: 18 patients, 68 physicians and 191 GP members participated. 'Overall survival' was the most important attribute, followed by 'risk of serious infection' and 'progression-free survival' among physicians and the GP. In contrast, 'treatment administration' was the second most important attribute to patients, followed by 'risk of serious infection.' Conclusion: Preferences for characteristics differentiating treatments of r/r MCL varies between patients, physicians and members of the GP.
引用
收藏
页码:859 / 868
页数:10
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