Introduction to bacterial signal transduction networks

被引:0
作者
Eguchi, Yoko [1 ]
Utsumi, Ryutaro [1 ]
机构
[1] Kinki Univ, Dept Biosci, Grad Sch Agr, Nara 6318505, Japan
来源
BACTERIAL SIGNAL TRANSDUCTION: NETWORKS AND DRUG TARGETS | 2008年 / 631卷
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中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Transcriptional analysis using a DNA microarray is an extremely efficient method for analyzing two-component signal transduction networks. Here we introduce three such networks in Escherichia coli that were clarified using a DNA microarray: a PhoQ/PhoP system that senses extracellular Mg2+ and controls the gene expression for adaptation to environmental Me, deprivation (Mg2+ stimulon); an EvgS/EvgA signal transduction system that activates expression of multiple drug efflux pumps and acid resistance genes; and a signal transduction cascade between EvgS/EvgA and PhoQ/PhoP.
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页码:1 / 6
页数:6
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