Nonsteroidal antiinflammatory drugs, eicosanoids, and colorectal cancer prevention

被引：189

作者：

DuBois, RN

Giardiello, FM

Smalley, WE

机构：

[1] VANDERBILT UNIV, MED CTR, DEPT CELL BIOL, VET AFFAIRS MED CTR, NASHVILLE, TN 37232 USA

[2] JOHNS HOPKINS UNIV, SCH MED, DEPT MED, BALTIMORE, MD 21205 USA

[3] VANDERBILT UNIV, MED CTR, DEPT MED, VET AFFAIRS MED CTR, NASHVILLE, TN 37232 USA

来源：

GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 1996年 / 25卷 / 04期

关键词：

D O I：

10.1016/S0889-8553(05)70274-0

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to be one of the most affective class of chemoprotective agents to date. Most of the published studies have evaluated gastrointestinal malignancies. Here the authors review the clinical, epidemiologic, and laboratory data evaluating the affects of NSAIDs in cancer prevention. The authors hope that through a rigorous evaluation of past work and future experimentation the molecular basis for cancer chemoprevention by these agents will be understood.

引用

页码：773 / +

页数：1

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