Pancreatic enzyme replacement therapy after gastric resection: An update

被引:22
作者
Antonini, Filippo [1 ]
Crippa, Stefano [2 ]
Falconi, Massimo [2 ]
Macarri, Giampiero [1 ]
Pezzilli, Raffaele [3 ]
机构
[1] Polytech Univ Marche, A Murri Hosp, Dept Gastroenterol, Fermo, Italy
[2] Vita E Salute Univ, San Raffaele Sci Inst, Pancreas Translat & Clin Res Ctr, Div Pancreat Surg, Milan, Italy
[3] St Orsola Malpighi Hosp, Dept Digest Dis & Internal Med, Bologna, Italy
关键词
Exocrine pancreatic insufficiency; Gastrectomy; Pancreatic enzyme; Surgery; TOTAL GASTRECTOMY; EXOCRINE INSUFFICIENCY; SUBTOTAL GASTRECTOMY; BACTERIAL OVERGROWTH; FECAL ELASTASE-1; GUIDELINES; RECOMMENDATIONS; MALNUTRITION; ASSOCIATION; MANAGEMENT;
D O I
10.1016/j.dld.2017.10.025
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Exocrine pancreatic insufficiency (EPI) is one of the possible mechanisms of fat maldigestion following gastric surgery, together with reduced food intake, loss of gastric reservoir, small bowel bacterial overgrowth and rapid small bowel transit. Oral pancreatic enzyme replacement therapy (PERT) is the mainstay of treatment for EPI. The efficacy and safety of pancreatic enzyme substitution in patients following gastric resection remains unclear. This review article summarizes relevant studies addressing PERT after gastric resection. (c) 2017 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:1 / 5
页数:5
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