Primary Liver Cancers - Hepatocellular Carcinoma and Cholangiocarcinoma

Malignant liver tumors are often discovered as an incidental finding on sonography. Hepatoceltular carcinoma (HCC) is the most common primary liver malignancy, followed by cholangiocellular carcinoma (CCC). The most employed diagnostic tests are MRI with gadolinium contrast medium or 3-phase CT abdomen. Biopsy of a hepatic nodule can be omitted if the radiologic and clinical presentation are typical. Patients with malignant liver tumors and /or unclear findings should present to a liver center. The most effective therapies for HCC and CCC include liver resection and liver transplantation. Only surgical oncologic R0 resection is curative. The therapy should be done by a multidisciplinary team. If primary surgery of the lesion is not possible, interventional or sytemic chemotherapy can also be helpful.