You AhR What You Eat: Linking Diet and Immunity

被引：38

作者：

Hooper, Lora V. ^{[1
,2
]}

机构：

[1] Univ Texas SW Med Ctr Dallas, Howard Hughes Med Inst, Dallas, TX 75390 USA

[2] Univ Texas SW Med Ctr Dallas, Dept Immunol, Dallas, TX 75390 USA

来源：

CELL | 2011年 / 147卷 / 03期

关键词：

ARYL-HYDROCARBON RECEPTOR; DELTA T-CELLS; HOMEOSTASIS; EXPRESSION; SYSTEM;

D O I：

10.1016/j.cell.2011.10.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The aryl hydrocarbon receptor (AhR) is responsible for the toxic effects of environmental pollutants such as dioxin, but little is known about its normal physiological functions. Li et al. (2011) now show that specific dietary compounds present in cruciferous vegetables act through the AhR to promote intestinal immune function, revealing AhR as a critical link between diet and immunity.

引用

收藏

页码：486 / 490

页数：5

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