Microwave Assisted Synthesis of 2, 6-Substituted Aromatic-Aminopurine Derivatives

被引：7
作者：
Lu, Hong-Fei [1 ]
Zhang, Liang-Ze [1 ]
Wu, Ding-Ming [1 ]
Zhou, Jun-Tao [1 ]
机构：
[1] Jiangsu Univ Sci & Technol, Dept Appl Chem, Sch Mat Sci & Engn, Zhenjiang, Peoples R China
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2011年 / 48卷 / 05期
关键词：
2,6,9-TRISUBSTITUTED PURINES; ANTITUMOR; SERIES;
D O I：
10.1002/jhet.629
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of novel 2, 6-diaromatic-aminopurines (6a-6t) have been synthesized from guanine and characterized fully. The effects of different catalysts on the N-alkylation of 2-position of purine ring were discussed.
引用
收藏
页码：1140 / 1144
页数：5
相关论文
共 50 条
[41]   Microwave-assisted solvent-free synthesis of 2-styrylquinolines in the presence of zinc chloride [J].
Li, V. M. ;
Gavrishova, T. N. ;
Budyka, M. F. .
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2012, 48 (06) :823-828
[42]   A diversity oriented, microwave assisted synthesis of N-substituted 2-hydro-4-amino-pyrido[2,3-d]pyrimidin-7(8H)-ones [J].
Mont, Nuria ;
Teixido, Jordi ;
Borrell, Jose I. .
MOLECULAR DIVERSITY, 2009, 13 (01) :39-45
[43]   Synthesis and antitumor activity of novel 6,7,8-trimethoxy N-aryl-substituted-4-aminoquinazoline derivatives [J].
Liu, Fang ;
Huai, Ziyou ;
Xia, Guotai ;
Song, Liuping ;
Li, Sha ;
Xu, Yulan ;
Hong, Kangjun ;
Yao, Mingyue ;
Liu, Gang ;
Huang, Yinjiu .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28 (14) :2561-2565
[44]   Synthesis and anti-microbial activity of some 1-substituted amino-4, 6-dimethyl-2-oxo-pyridine-3-carbonitrile derivatives [J].
Khidre, Rizk E. ;
Abu-Hashem, Ameen A. ;
El-Shazly, Mohamed .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 46 (10) :5057-5064
[45]   Synthesis and blood glucose lowering activity of some novel benzenesulfonylurea derivatives substituted with 6-aryl-4,5-dihyropyridazin-3(2H)-ones [J].
Bashir, Rafia ;
Ovais, Syed ;
Yaseen, Shafiya ;
Hamid, Hinna ;
Alam, M. S. ;
Samim, Mohammed ;
Javed, Kalim .
MEDICINAL CHEMISTRY RESEARCH, 2012, 21 (12) :4352-4356
[46]   Synthesis and blood glucose lowering activity of some novel benzenesulfonylthiourea derivatives substituted with 6-aryl-4,5-dihyropyridazin-3(2H)-ones [J].
Bashir, Rafia ;
Yaseen, Shafiya ;
Ovais, Syed ;
Hamid, Hinna ;
Alam, M. S. ;
Samim, Mohammad ;
Javed, Kalim .
MEDICINAL CHEMISTRY RESEARCH, 2012, 21 (04) :428-436
[47]   Reactivity of 2-substituted hydrazinecarbothioamides towards tetracyanoethylene and convenient synthesis of (5-amino-2-diazenylthiazolylmethylene) malononitrile derivatives [J].
Hassan, Alaa A. ;
Mohamed, Nasr K. ;
El-Shaieb, Kamal M. A. ;
Tawfeek, Hendawy N. ;
Braese, Stefan ;
Nieger, Martin .
ARKIVOC, 2016, :163-171
[48]   How do reaction conditions affect the enantiopure synthesis of 2-substituted-1,4-benzodioxane derivatives? [J].
Straniero, Valentina ;
Casiraghi, Andrea ;
Fumagalli, Laura ;
Valoti, Ermanno .
CHIRALITY, 2018, 30 (07) :943-950
[49]   Synthesis and Bioactivities of Novel Thiazole Amide Derivatives Containing a 2-Substituted-1,3-thiazolidine Ring [J].
Dai, Hong ;
Liu, Jianbing ;
Miao, Wenke ;
Wu, Shanshan ;
Zhang, Xin ;
Wang, Tingting ;
Fang, Jianxin .
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2011, 31 (11) :1943-1948
[50]   Efficient and mild synthesis of highly substituted 2,5-dihydrofuran and furan derivatives via stepwise reaction [J].
Wang, Tiantian ;
Liu, Jia ;
Lv, Zhiliang ;
Zhong, Hanyu ;
Chen, Huan ;
Niu, Chunjuan ;
Li, Ke .
TETRAHEDRON, 2011, 67 (19) :3476-3482
12345