Leukonychia totalis associated with multiple pilar cysts: report of a five-generation family: FLOTCH syndrome?

被引：7

作者：

Rodriguez-Lojo, Romina ^{[1
]}

Del Pozo, Jesus ^{[1
]}

Sacristan, Felipe ^{[2
]}

Barja, Juan ^{[1
]}

Pineyro-Molina, Francisca ^{[1
]}

Perez-Varela, Lucia ^{[1
]}

机构：

[1] CHU A Coruna, Dept Dermatol, La Coruna 15001, Spain

[2] CHU A Coruna, Dept Pathol, La Coruna 15006, Spain

来源：

EUROPEAN JOURNAL OF DERMATOLOGY | 2011年 / 21卷 / 04期

关键词：

leukonychia; pilar cysts; nail; FLOTCH syndrome; hair; Bauer syndrome; SEBACEOUS CYSTS; CONGENITAL LEUKONYCHIA; PARTIALIS;

D O I：

10.1684/ejd.2011.1369

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The association of familial totalis leukonychia with multiple pilar cysts is a rare condition that could represent a separate syndromic entity. Since Bauer described a family with totalis leukonychia and sebaceous cysts in 1920, only four new affected families have been reported. We report a five-generation family with a total leukonychia and multiple pilar cysts on the scalp. The hypothesis of a deficiency of a gene regulating the structure of keratin has been postulated but the exact genetic mechanism has not been yet determined. In our family, no other keratinizing structures were involved.

引用

页码：484 / 486

页数：3

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