The Challenges of Vaccine Development against a New Virus during a Pandemic

被引：79

作者：

Diamond, Michael S. ^{[1
,2
,3
,4
]}

Pierson, Theodore C. ^{[5
]}

机构：

[1] Washington Univ, Dept Med, Sch Med, St Louis, MO 63110 USA

[2] Washington Univ, Dept Mol Microbiol, Sch Med, St Louis, MO 63110 USA

[3] Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA

[4] Washington Univ, Ctr Human Immunol & Immunotherapy Programs, Sch Med, St Louis, MO 63110 USA

[5] NIAID, NIH, Lab Viral Dis, Bethesda, MD 20892 USA

来源：

CELL HOST & MICROBE | 2020年 / 27卷 / 05期

关键词：

SPIKE; SARS;

D O I：

10.1016/j.chom.2020.04.021

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The rapid emergence of a highly pathogenic, readily transmissible coronavirus has resulted in a global pandemic, affecting millions and destabilizing economies. This catastrophe triggered a clarion call for the immediate deployment of a protective vaccine. We describe the unique challenges of developing a vaccine against SARS-CoV-2 in a pandemic setting.

引用

页码：699 / 703

页数：5

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