Pharmaceutical company funding and its consequences: A qualitative systematic review

被引：185

作者：

Sismondo, Sergio ^{[1
]}

机构：

[1] Queens Univ, Dept Philosophy, Kingston, ON K7L 3N6, Canada

来源：

CONTEMPORARY CLINICAL TRIALS | 2008年 / 29卷 / 02期

关键词：

industry funding; sponsorship; pharmaceutical companies; bias;

D O I：

10.1016/j.cct.2007.08.001

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

This article systematically reviews published studies of the association of pharmaceutical industry funding and clinical trial results, as well a few closely related studies. It reviews two earlier results, and surveys the recent literature. Results are clear: Pharmaceutical company sponsorship is strongly associated with results that favor the sponsors' interests. (C) 2007 Elsevier Inc. All rights reserved.

引用

页码：109 / 113

页数：5

共 30 条

[1] Association of funding and conclusions in randomized drug trials - A reflection of treatment effect or adverse events? [J].

Als-Nielsen, B ;

Chen, WD ;

Gluud, C ;

Kjaergard, LL .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 290 (07) :921-928

[2]

Baird P, 2003, CAN MED ASSOC J, V168, P1267

[3] Quantitative analysis of sponsorship bias in economic studies of antidepressants [J].

Baker, CB ;

Johnsrud, MT ;

Crismon, ML ;

Rosenheck, R ;

Woods, SW .

BRITISH JOURNAL OF PSYCHIATRY, 2003, 183 :498-506

[4] Bias from industry trial funding? A framework, a suggested approach, and a negative result [J].

Barden, J ;

Derry, S ;

McQuay, HJ ;

Moore, RA .

PAIN, 2006, 121 (03) :207-218

[5] Scope and impact of financial conflicts of interest in biomedical research - A systematic review [J].

Bekelman, JE ;

Li, Y ;

Gross, CP .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 289 (04) :454-465

[6] Bias in published cost effectiveness studies: systematic review [J].

Bell, CM ;

Urbach, DR ;

Ray, JG ;

Bayoumi, A ;

Rosen, AB ;

Greenberg, D ;

Neumann, PJ .

BMJ-BRITISH MEDICAL JOURNAL, 2006, 332 (7543) :699-701

[7] Potential conflicts of interest in vaccine economics research: a commentary witha case study of pneumococcal conjugate vaccination [J].

Beutels, P .

VACCINE, 2004, 22 (25-26) :3312-3322

[8]

Bhandari M, 2004, CAN MED ASSOC J, V170, P477

[9] Association of industry sponsorship to published outcomes in gastrointestinal clinical research [J].

Brown, Alphonso ;

Kraft, Daniel ;

Schmitz, Sara M. ;

Sharpless, Virginia ;

Martin, Christopher ;

Shah, Ritesh ;

Shaheen, Nicholas J. .

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2006, 4 (12) :1445-1451

[10]

Brown James Robert, 2004, EPISTEME, V1, P49

← 1 2 3 →