Treatment of acrodermatitis continua of Hallopeau with oral propylthiouracil and methotrexate

被引：10

作者：

Chowdhury, MMU ^{[1
]}

Motley, RJ ^{[1
]}

机构：

[1] Univ Wales Hosp, Dept Dermatol, Cardiff CF14 4XW, S Glam, Wales

来源：

CLINICAL AND EXPERIMENTAL DERMATOLOGY | 2001年 / 26卷 / 08期

关键词：

D O I：

10.1046/j.1365-2230.2001.00911.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

A 71-year-old man with acrodermatitis continua of Hallopeau was treated successfully with a combination of oral propylthiouracil and methotrexate. After 14 weeks, he developed acute pancytopenia, an uncommon idiosyncratic side-effect of propylthiouracil, and presented with a life-threatening methicillin-resistant Staphylococcus aureus pneumonia. This illustrates the potential value and associated risks of propylthiouracil in the management of this difficult condition.

引用

页码：657 / 660

页数：4

共 12 条

[1]

CAMP RDR, 1998, TXB DERMATOLOGY, V2, P1633

[2] Propylthiouracil hypersensitivity: Report of two patients with vasculitis and review of the literature [J].

Chastain, MA ;

Russo, GG ;

Boh, EE ;

Chastain, JB ;

Falabella, A ;

Millikan, LE .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1999, 41 (05) :757-764

[3]

Chowdhury MMU, 2001, J DERMATOL TREAT, V12, P81

[4]

Cooper DS., 1996, THYROID, P895

[5] PROPYLTHIOURACIL IN PSORIASIS - RESULTS OF AN OPEN TRIAL [J].

ELIAS, AN ;

GOODMAN, MM ;

LIEM, WH ;

BARR, RJ .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1993, 29 (01) :78-81

[6] SERUM ICAM-1 CONCENTRATIONS IN PATIENTS WITH PSORIASIS TREATED WITH ANTITHYROID THIOUREYLENES [J].

ELIAS, AN ;

GOODMAN, MM ;

ROHAN, MK .

CLINICAL AND EXPERIMENTAL DERMATOLOGY, 1993, 18 (06) :526-529

[7] A CONTROLLED TRIAL OF TOPICAL PROPYLTHIOURACIL IN THE TREATMENT OF PATIENTS WITH PSORIASIS [J].

ELIAS, AN ;

DANGARAN, K ;

BARR, RJ ;

ROHAN, MK ;

GOODMAN, MM .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1994, 31 (03) :455-458

[8] EFFECT OF ORALLY-ADMINISTERED ANTITHYROID THIOUREYLENES ON PCNA AND P53 EXPRESSION IN PSORIATIC LESIONS [J].

ELIAS, AN ;

BARR, RJ ;

ROHAN, MK ;

DANGARAN, K .

INTERNATIONAL JOURNAL OF DERMATOLOGY, 1995, 34 (04) :280-283

[9] LOW-DOSE ORAL PROPYLTHIOURACIL IN THE TREATMENT OF PLAQUE PSORIASIS [J].

ELIAS, AR ;

BARR, RJ .

INTERNATIONAL JOURNAL OF DERMATOLOGY, 1995, 34 (07) :519-520

[10] Fortnightly review - Controversial aspects of thyroid disease [J].

Hanna, FWF ;

Lazarus, JH ;

Scanlon, MF .

BRITISH MEDICAL JOURNAL, 1999, 319 (7214) :894-899

← 1 2 →