Pectin - An emerging new bioactive food polysaccharide

被引:314
作者
Maxwell, Ellen G. [1 ]
Belshaw, Nigel J. [1 ]
Waldron, Keith W. [1 ]
Morris, Victor J. [1 ]
机构
[1] AFRC, Inst Food Res, Norwich Res Pk,Colney Lane, Norwich NR4 7UA, Norfolk, England
基金
英国生物技术与生命科学研究理事会;
关键词
MODIFIED CITRUS PECTIN; HUMAN BREAST-CARCINOMA; GALECTIN-3; EXPRESSION; COLORECTAL-CANCER; PROSTATE-CANCER; SPONTANEOUS METASTASIS; TUMOR PROGRESSION; CELL-MIGRATION; MELANOMA-CELLS; BETA-GLUCAN;
D O I
10.1016/j.tifs.2011.11.002
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Pectin is a constituent of the cell walls of fruits and vegetables, and provides an important source of dietary fibre, as well as being a functional ingredient in processed foods. In addition to the health benefits associated with dietary fibre, new health claims are emerging, particularly with regard to the bioactive roles for modified pectin as an anti-cancer agent. These suggest that the modification creates molecular fragments, some of which may bind to and inhibit the various actions of the pro-metastatic protein galectin-3. The evidence for such a mechanism and the nature of the bioactive fragments will be discussed.
引用
收藏
页码:64 / 73
页数:10
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