Serum levels of S100B are decreased in chronic starvation and normalize with weight gain

被引：26

作者：

Holtkamp, Kristian ^{[1
]}

Buehren, Katharina ^{[1
]}

Ponath, Gerald ^{[2
]}

von Eiff, Christoph ^{[3
]}

Herpertz-Dahlmann, Beate ^{[1
]}

Hebebrand, Johannes ^{[4
]}

Rothermundt, Matthias ^{[2
]}

机构：

[1] Rhein Westfal TH Aachen, Dept Child & Adolescent Psychiat & Psychotherapy, D-52074 Aachen, Germany

[2] Univ Munster, Sch Med, Dept Psychiat, Munster, Germany

[3] Univ Munster, Sch Med, Inst Med Microbiol, Munster, Germany

[4] Univ Duisburg Essen, Dept Child & Adolescent Psychiat & Psychotherapy, Essen, Germany

来源：

JOURNAL OF NEURAL TRANSMISSION | 2008年 / 115卷 / 06期

关键词：

eating disorder; fasting; starvation; S100; anorexia nervosa;

D O I：

10.1007/s00702-008-0041-8

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

S100B protein is mainly synthesized in glial cells and modulates the balance between cell proliferation and differentiation in neurons and glial cells. However, S100B is not CNS-specific since its production was detected in numerous non-cerebral tissues e.g. adipocytes. In this study we investigated the influence of chronic fasting and subsequent weight gain on serum levels of S100B in patients with anorexia nervosa. We found that nutritional status was an important factor influencing serum levels of S100B.

引用

页码：937 / 940

页数：4

共 17 条

[1] High serum S100B levels for trauma patients without head injuries [J].

Anderson, RE ;

Hansson, LO ;

Nilsson, O ;

Dijlai-Merzoug, R ;

Settergren, G .

NEUROSURGERY, 2001, 48 (06) :1255-1258

[2]

Azmitia EC, 2002, PROG BRAIN RES, V136, P87

[3] Increase in serum S100B protein level after a swimming race. [J].

Dietrich, MO ;

Tort, AB ;

Schaf, DV ;

Farina, M ;

Gonçalves, CA ;

Souza, DO ;

Portela, LV .

CANADIAN JOURNAL OF APPLIED PHYSIOLOGY-REVUE CANADIENNE DE PHYSIOLOGIE APPLIQUEE, 2003, 28 (05) :710-716

[4]

Fichter MM, 1998, INT J EAT DISORDER, V24, P227, DOI 10.1002/(SICI)1098-108X(199811)24:3<227::AID-EAT1>3.3.CO

[5]

2-O

[6] Pediatric concentrations of S100B protein in blood: Age- and sex-related changes [J].

Gazzolo, D ;

Michetti, F ;

Bruschettini, M ;

Marchese, N ;

Lituania, M ;

Mangraviti, S ;

Pedrazzi, E ;

Bruschettini, P .

CLINICAL CHEMISTRY, 2003, 49 (06) :967-970

[7] The effect of therapeutically induced weight gain on plasma leptin levels in patients with anorexia nervosa [J].

Holtkamp, K ;

Hebebrand, J ;

Mika, C ;

Grzella, I ;

Heer, M ;

Heussen, N ;

Herpertz-Dahlmann, B .

JOURNAL OF PSYCHIATRIC RESEARCH, 2003, 37 (02) :165-169

[8] CSF 5-HIAA CONCENTRATIONS IN ANOREXIA-NERVOSA - REDUCED VALUES IN UNDERWEIGHT SUBJECTS NORMALIZE AFTER WEIGHT-GAIN [J].

KAYE, WH ;

GWIRTSMAN, HE ;

GEORGE, DT ;

JIMERSON, DC ;

EBERT, MH .

BIOLOGICAL PSYCHIATRY, 1988, 23 (01) :102-105

[9] β-hydroxy-butyrate alters the extracellular content of S100B in astrocyte cultures [J].

Leite, M ;

Frizzo, JK ;

Nardin, P ;

de Almeida, LMV ;

Tramontina, F ;

Gottfried, C ;

Gonçalves, CA .

BRAIN RESEARCH BULLETIN, 2004, 64 (02) :139-143

[10] Serum S100B protein is increased in fasting rats [J].

Netto, Cristina B. O. ;

Conte, Sabrina ;

Leite, Marina C. ;

Pires, Caroline ;

Martins, Tiago L. ;

Vidal, Penelope ;

Benfato, Mara S. ;

Giugliani, Roberto ;

Gonçalves, Carlos-Alberto .

ARCHIVES OF MEDICAL RESEARCH, 2006, 37 (05) :683-686

← 1 2 →