Febrile infection-related epilepsy syndrome (FIRES): Does duration of anesthesia affect outcome?

被引:33
作者
Kramer, Uri [1 ]
Chi, Ching-Shiang [2 ]
Lin, Kuang-Lin [3 ,4 ]
Specchio, Nicola [5 ]
Sahin, Mustafa [8 ,9 ]
Olson, Heather [8 ,9 ]
Kluger, Gerhard [6 ]
van Baalen, Andreas [7 ]
机构
[1] Tel Aviv Univ, Tel Aviv Sourasky Med Ctr, Pediat Epilepsy Unit, IL-69978 Tel Aviv, Israel
[2] Tungs Taichung MetroHarbor Hosp, Dept Pediat, Taichung, Taiwan
[3] Chang Gung Childrens Hosp, Div Pediat Neurol, Tao Yuan, Taiwan
[4] Chang Gung Mem Hosp, Tao Yuan, Taiwan
[5] Bambino Gesu Pediat Hosp, Div Neurol, Rome, Italy
[6] BHZ Vogtareuth, Neuropediat Dept, Vogtareuth, Germany
[7] Univ Kiel, Univ Med Ctr Schleswig Holstein, Dept Neuropediat, Kiel, Germany
[8] Childrens Hosp, Dept Neurol, Div Epilepsy & Clin Neurophysiol, Boston, MA 02115 USA
[9] Harvard Univ, Sch Med, Boston, MA USA
关键词
Epilepsy; Children; Refractory; Status epilepticus; REFRACTORY STATUS EPILEPTICUS; PRESUMED ENCEPHALITIS; CHILDREN; ENCEPHALOPATHY; CHILDHOOD; RAT;
D O I
10.1111/j.1528-1167.2011.03230.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We conducted a retrospective multicenter study on children who had been included in eight studies published between November 2001 and July 2010 to explore the correlations between burst-suppression coma (BSC) with outcome in febrile infection-related epilepsy syndrome (FIRES). The 77 enrolled patients presented with prolonged refractory status epilepticus. BSC was induced in 46 patients. Cognitive levels at follow-up were significantly associated with duration of a BSC (p = 0.005). The outcome of FIRES is poor. Treatment by inducing a prolonged BSC was associated with a worse cognitive outcome.
引用
收藏
页码:28 / 30
页数:3
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