An experimental study on the application of radionuclide imaging in repair of the bone defect

被引：0

作者：

Zhu, Weimin ^{[1
]}

Wang, Daping ^{[1
]}

Zhang, Xiaojun ^{[2
]}

Lu, Wei ^{[1
]}

Liu, Jianquan ^{[1
]}

Peng, Liangquan ^{[1
]}

Li, Hao ^{[1
]}

Han, Yun ^{[1
]}

Zeng, Yanjun ^{[2
]}

机构：

[1] Shenzhen Second Peoples Hosp, Dept Sports Med, Shenzhen 518035, Peoples R China

[2] Beijing Univ Technol, Beijing 100124, Peoples R China

来源：

BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES | 2011年 / 11卷 / 03期

关键词：

hydroxyapatite; nanometer; artificial bone; bone defect; radionuclide imaging;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The aim of our study was to validate the effect of radionuclide imaging in early monitoring of the bone's reconstruction, the animal model of bone defect was made on the rabbits repaired with HA artificial bone. The ability of bone defect repair was evaluated by using radionuclide bone imaging at 2, 4, 8 and 12 weeks postoperatively. The results indicate that the experimental group stimulated more bone formation than that of the control group. The differences of the bone reconstruction ability were statistically significant (p<0.05). The nano-HA artificial has good bone conduction, and it can be used for the treatment of bone defects. Radionuclide imaging may be an effective and first choice method for the early monitoring of the bone's reconstruction. (C) 2011 Association of Basic Medical Sciences of FBI H. All rights reserved

引用

页码：163 / 168

页数：6

共 16 条

[1]

Dorner-Reisel A, 2002, Biomed Tech (Berl), V47 Suppl 1 Pt 1, P397

[2]

DORNERREISEL A, 2002, BIOMED TECH 2 S1, V47, P400

[3] BONE-SEEKING RADIONUCLIDES - INVIVO STUDY OF FACTORS AFFECTING SKELETAL UPTAKE [J].

GENANT, HK ;

BAUTOVICH, GJ ;

SINGH, M ;

LATHROP, KA ;

HARPER, PV .

RADIOLOGY, 1974, 113 (02) :373-382

[4] PREOPERATIVE TC-99M-MDP SCINTIMETRY OF FEMORAL-NECK FRACTURES [J].

HOLMBERG, S ;

THORNGREN, KG .

ACTA ORTHOPAEDICA SCANDINAVICA, 1984, 55 (04) :430-435

[5]

Iwakami T, 2002, BIO-MED MATER ENG, V12, P249

[6]

NUTTON RW, 1984, ORTHOP RES, V2, P67

[7]

NUZZO G, 2010, J CRANIOFAC SURG, V21, P1170

[8]

SAN SB, 1996, NUCL TECHNIQUES, V19, P31

[9] Clinical effectiveness of Tc-99m-diphosphonate scintigraphy of revascularized iliac crest flaps [J].

Smeele, LE ;

Hoekstra, OS ;

Winters, HAH ;

Leemans, CR .

INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 1996, 25 (05) :366-369

[10]

SUN MY, 2003, ORTHOP J CHIN, V11, P86

← 1 2 →