Anticancer and antimicrobial activities of scorpion venoms and their peptides

被引：12
作者：
Akef, Hassan M. [1 ]
机构：
[1] NORCB, Giza, Egypt
来源：
TOXIN REVIEWS | 2019年 / 38卷 / 01期
关键词：
Scorpion venom; scorpion peptides; antineoplastic agents; antibacterial agents; antifungal agents; antiviral agents; FUNCTIONAL-CHARACTERIZATION; STRUCTURAL-CHARACTERIZATION; CELL INVASION; MAPK PATHWAY; CHLOROTOXIN; APOPTOSIS; MIGRATION; PROTEIN; BMKN2; PROLIFERATION;
D O I：
10.1080/15569543.2017.1414847
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
Scorpion venom is a natural biological resource that contains several components, which are not only responsible for death but also have a potential therapeutic activity. Scorpion venom has been used as traditional and folk therapy in various pathophysiological conditions. Now, many scorpion venom components have been purified and identified. Based on the available structural and functional information of these components, the scientists can produce new venom-derived medications with potential therapeutic activity against many important diseases. This review focused on the importance of scorpion venoms and their peptides against cancer and microbes.
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收藏
页码：41 / 53
页数：13
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