The oxidative coupling of benzylic compounds catalyzed by 2,3-dichloro-5,6-dicyano-benzoquinone and sodium nitrite using molecular oxygen as a co-oxidant

被引：22

作者：

Cheng, Dongping ^{[1
]}

Yuan, Kun ^{[1
]}

Xu, Xiaoliang ^{[2
]}

Yan, Jizhong ^{[1
]}

机构：

[1] Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Zhejiang, Peoples R China

[2] Zhejiang Univ Technol, Coll Chem Engn & Mat Sci, Hangzhou 310014, Zhejiang, Peoples R China

来源：

TETRAHEDRON LETTERS | 2015年 / 56卷 / 13期

关键词：

C-C coupling; DDQ; Oxidation; Molecular oxygen; SP(3) C-H; METAL-FREE; HIGHLY EFFICIENT; SELECTIVE OXIDATION; CARBOXYLIC-ACIDS; MILD CONDITIONS; BOND FORMATION; DDQ; ACTIVATION; ETHERS;

D O I：

10.1016/j.tetlet.2015.02.018

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Catalyzed by DDQ and NaNO2, the oxidative coupling between benzylic compounds and 1,3-dicarbonyls in the presence of molecular oxygen and HCOOH was developed. The 1% catalytic amount of DDQ is enough to complete the reaction. This system shows high efficiency and the coupling products are obtained in good to excellent yields within half an hour. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：1641 / 1644

页数：4

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