Treatment of chronic left ventricular assist device infection with local application of bacteriophages

被引：35

作者：

Mulzer, Johanna ^{[1
]}

Trampuz, Andrej ^{[2
,3
,4
,5
]}

Potapov, Evgenij V. ^{[1
,6
]}

机构：

[1] German Heart Ctr Berlin, Dept Cardiothorac & Vasc Surg, Augustenburger Pl 1, D-13353 Berlin, Germany

[2] Charite Univ Med Berlin, Ctr Musculoskeletal Surg, Berlin, Germany

[3] Free Univ Berlin, Berlin, Germany

[4] Humboldt Univ, Berlin, Germany

[5] Berlin Brandenburg Ctr Regenerat Therapies, Berlin, Germany

[6] DZHK German Ctr Cardiovasc Res, Partner Site, Berlin, Germany

来源：

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY | 2020年 / 57卷 / 05期

关键词：

Left ventricular assist device-associated infections; Methicillin-susceptible Staphylococcus aureus; Bacteriophages;

D O I：

10.1093/ejcts/ezz295

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Left ventricular assist device-associated infections represent a major complication during long-term support. Driveline exit site infections harbour the risk of ascending into the pump, causing deep-seated infections. We report on the successful treatment of a chronic recurrent left ventricular assist device pump-associated infection by the local application of bacteriophages as adjunct to standard surgical and antimicrobial treatment.

引用

页码：1003 / 1004

页数：2

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