Risk factors for mortality in end-stage kidney disease patients under online-hemodiafiltration: three-year follow-up study

被引:4
作者
de Sousa-Martins, Pedro [1 ]
Moura, Alexandra [2 ]
Madureira, Jose [3 ]
Alija, Pablo [3 ]
Oliveira, Jose Gerardo [4 ]
Lopez, Martin [5 ]
Filgueiras, Madalena [6 ]
Amado, Leonilde [7 ]
Sameiro-Faria, Maria [7 ]
Miranda, Vasco [7 ]
Mesquita, Edgar [8 ]
Teixeira, Laetitia [1 ]
Poveda, Veronica [1 ]
Lobato, Luisa [1 ,9 ,10 ]
Santos-Silva, Alice [11 ,12 ]
Costa, Elisio [11 ,12 ]
机构
[1] Univ Porto, Inst Ciencias Biomed Abel Salazar, Porto, Portugal
[2] Univ Catolica Portuguesa, Inst Ciencias Saude, Porto, Portugal
[3] Clin Hemodialise NefroServe, Barcelos, Portugal
[4] Ctr Hosp Porto, Porto, Portugal
[5] Clin Hemodialise Felgueira, Felgueiras, Portugal
[6] Clin Hemodialise Gondomar, Gondomar, Portugal
[7] Clin Hemodialise NephroCare, Maia, Portugal
[8] Univ Minho, Nucleo Estudantes Estat, Braga, Portugal
[9] Ctr Hosp Porto, Serv Nefrol, Porto, Portugal
[10] Ctr Hosp Porto, Dept Ensino Formacao & Invest, Porto, Portugal
[11] Univ Porto, Fac Farm, Dept Ciencias Biol, Lab Bioquim, Rua Jorge Viterbo Ferreira 228, P-4050313 Porto, Portugal
[12] Univ Porto, REQUIMTE, UCIBIO, Porto, Portugal
关键词
End-stage kidney disease; health-related quality of life; inflammation; iron metabolism; mortality; nutritional status; online-hemodiafiltration; QUALITY-OF-LIFE; RENAL-DISEASE; CARDIOVASCULAR-DISEASE; HEMODIALYSIS-PATIENTS; SERUM-ALBUMIN; DIALYSIS; EPIDEMIOLOGY; HEALTH; HOSPITALIZATION; ASSOCIATION;
D O I
10.3109/1354750X.2016.1160428
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The aim of this work was to evaluate the predictors of mortality in a group of end-stage kidney disease (ESRD) patients under dialysis, by performing a three-year follow-up study. From the 236 patients included in this study, 54 patients died during the three-year follow-up period. Our data showed that the risk of death was higher in patients presenting lower levels of mean cell hemoglobin concentration, transferrin, and albumin. Our study showed that poor nutritional status and an inflammatory-induced iron depleted erythropoiesis are important factors for mortality in these patients.
引用
收藏
页码:544 / 550
页数:7
相关论文
共 34 条
[1]  
Bayoumi Magda, 2013, Saudi J Kidney Dis Transpl, V24, P254
[2]   Mortality risk for patients receiving hemodiafiltration versus hemodialysis: European results from the DOPPS [J].
Canaud, B. ;
Bragg-Gresham, J. L. ;
Marshall, M. R. ;
Desmeules, S. ;
Gillespie, B. W. ;
Depner, T. ;
Klassen, P. ;
Port, F. K. .
KIDNEY INTERNATIONAL, 2006, 69 (11) :2087-2093
[3]   Cardiovascular mortality in end-stage renal disease [J].
Collins, AJ .
AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2003, 325 (04) :163-167
[4]   Role of prohepcidin, inflammatory markers and iron status in resistance to rhEPO therapy in hemodialysis patients [J].
Costa, Elisio ;
Pereira, Brian J. G. ;
Rocha-Pereira, Petronila ;
Rocha, Susana ;
Reis, Flavio ;
Castro, Elisabeth ;
Teixeira, Frederico ;
Miranda, Vasco ;
Faria, Maria do Sameiro ;
Loureiro, Alfredo ;
Quintanilha, Alexandre ;
Belo, Luis ;
Santos-Silva, Alice .
AMERICAN JOURNAL OF NEPHROLOGY, 2008, 28 (04) :677-683
[5]   Risk Factors for Mortality in Hemodialysis Patients: Two-Year Follow-Up Study [J].
do Sameiro-Faria, Maria ;
Ribeiro, Sandra ;
Costa, Elisio ;
Mendonca, Denisa ;
Teixeira, Laetitia ;
Rocha-Pereira, Petronila ;
Fernandes, Joao ;
Nascimento, Henrique ;
Kohlova, Michaela ;
Reis, Flavio ;
Amado, Leonilde ;
Bronze-da-Rocha, Elsa ;
Miranda, Vasco ;
Quintanilha, Alexandre ;
Belo, Luis ;
Santos-Silva, Alice .
DISEASE MARKERS, 2013, 2013 :791-798
[6]  
Ferreira Pedro Lopes, 2012, Rev. Port. Sau. Pub., V30, P163
[7]  
Ferreira Pedro Lopes, 2010, Rev. Port. Sau. Pub., V28, P31
[8]   Clinical epidemiology of cardiovascular disease in chronic renal disease [J].
Foley, RN ;
Parfrey, PS ;
Sarnak, MJ .
AMERICAN JOURNAL OF KIDNEY DISEASES, 1998, 32 (05) :S112-S119
[9]   Resistance to Recombinant Human Erythropoietin Therapy in a Rat Model of Chronic Kidney Disease Associated Anemia [J].
Garrido, Patricia ;
Ribeiro, Sandra ;
Fernandes, Joao ;
Vala, Helena ;
Rocha-Pereira, Petronila ;
Bronze-da-Rocha, Elsa ;
Belo, Luis ;
Costa, Elisio ;
Santos-Silva, Alice ;
Reis, Flavio .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 17 (01)
[10]   DEVELOPMENT OF THE KIDNEY-DISEASE QUALITY-OF-LIFE (KDQOL(TM)) INSTRUMENT [J].
HAYS, RD ;
KALLICH, JD ;
MAPES, DL ;
COONS, SJ ;
CARTER, WB .
QUALITY OF LIFE RESEARCH, 1994, 3 (05) :329-338