The role of the neutrophil and phagocytosis in infection caused by Helicobacter pylori

被引:37
作者
Allen, LAH [1 ]
机构
[1] Univ Iowa, Dept Med, Div Infect Dis, Iowa City, IA 52242 USA
关键词
D O I
10.1097/00001432-200106000-00005
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Recent advances in our understanding of Helicobacter pylori- phagocyte interactions indicate that these organisms actively modulate phagocyte function in order to retard phagocytosis, while simultaneously inducing a strong respiratory burst. The central players in this dynamic include H. pylori neutrophil activating protein and factors that are associated with the cag pathogenicity island type IV secretion apparatus. Additionally, catalase, alkyl hydroperoxide reductase, and factors that are unique to type I strains allow bacteria to resist phagocytic killing. Curr Opin Infect Dis 14:273-277, (C) 2001 Lippincott Williams & Wilkins.
引用
收藏
页码:273 / 277
页数:5
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