Challenges in the treatment of psoriasis in childhood

被引：3

作者：

Cvenkel, Klara ^{[1
]}

Zorko, Mateja Starbek ^{[1
,2
]}

机构：

[1] Univ Med Ctr Ljubljana, Dept Dermatovenereol, Ljubljana, Slovenia

[2] Univ Ljubljana, Fac Med, Ljubljana, Slovenia

来源：

ACTA DERMATOVENEROLOGICA ALPINA PANNONICA ET ADRIATICA | 2021年 / 30卷 / 03期

关键词：

pediatric psoriasis; topical therapy; systemic therapy; unapproved treatment; childhood; adolescence; PEDIATRIC PSORIASIS; EPIDEMIOLOGY; METHOTREXATE; ETANERCEPT; MANAGEMENT; CHILDREN; SAFETY;

D O I：

10.15570/actaapa.2021.26

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Psoriasis is a chronic, immune-mediated, inflammatory skin disease that affects up to 1.2% of children and adolescents. The treat-ment possibilities for pediatric psoriasis are usually based on the same principles as in adults. Most information on safety and efficacy has been derived from adult studies, but only some of the frequently used treatments have approval for use in children. Treatment options for psoriasis in children and adolescents are mostly off-label, with little available data on efficacy and safety, and so the treatment of pediatric psoriasis remains a challenge. In the future, new pediatric clinical trials should be undertaken to expand the therapeutic spectrum for psoriasis in children and adolescents.

引用

页码：105 / 108

页数：4

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