Sex differences in cough reflex

被引：10

作者：

Pleykova, J. ^{[1
,2
]}

Buday, T. ^{[1
,2
]}

Kayalcikova-Bogdanova, N. ^{[1
,2
]}

Ioan, I. ^{[3
,4
]}

Demoulin-Alexikova, S. ^{[3
,4
]}

机构：

[1] Comenius Univ, Jessenius Fac Med Martin, Dept Pathophysiol, Mala Hora 4C, Martin 03601, Slovakia

[2] Comenius Univ, Jessenius Fac Med Martin, Div Neurosci BioMed Martin, Martin 03601, Slovakia

[3] Univ Lorraine, Fac Med, Lab Physiol, DevAH EA3450, Nancy, France

[4] CHRU Nancy, Children Hosp, Dept Pediat Lung Funct Testing, Nancy, France

来源：

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY | 2017年 / 245卷

关键词：

Cough; Gender differences; Hormones; Hypersensitivity; URGE-TO-COUGH; REGIONAL BRAIN RESPONSE; AFFERENT NERVE SUBTYPES; GENDER-DIFFERENCES; MENSTRUAL-CYCLE; HYPERSENSITIVITY SYNDROME; RESPIRATORY SYMPTOMS; FEMALE PREPONDERANCE; MEDIATING COUGH; TRP CHANNELS;

D O I：

10.1016/j.resp.2016.12.001

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Majority of patients visiting cough clinics are postmenopausal women, who are affected by intractable cough for years. Why the cough reflex becomes exaggerated in women is not known. Basic research excludes females from the studies contributing to the sex bias which may be responsible for lack of understanding of "hypersensitive" cough in women. Biological and behavioural differences between women and men are the factors affecting cough physiology. Gender also shapes the patterns of behaviour and determines the character of environmental exposures which differs between sexes. The article offers an insight into the physiology of the cough, differences in the maturation of it and biological, social and behavioural factors contributing to the sex differences in cough. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：122 / 129

页数：8

共 138 条

[1] Rhinovirus upregulates transient receptor potential channels in a human neuronal cell line: implications for respiratory virus-induced cough reflex sensitivity [J].