Characterization of Moraxella (Branhamella) catarrhalis lbpB, lbpA, and lactoferrin receptor orf3 isogenic mutants

被引：38
作者：
Bonnah, RA
Wong, H
Loosmore, SM
Schryvers, AB
机构：
[1] Univ Calgary, Dept Microbiol & Infect Dis, Hlth Sci Ctr, Calgary, AB T2N 4N1, Canada
[2] Pasteur Merieux Connaught Canada Res, Toronto, ON M2R 3T4, Canada
来源：
INFECTION AND IMMUNITY | 1999年 / 67卷 / 03期
关键词：
D O I：
10.1128/IAI.67.3.1517-1520.1999
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Pathogenic members of the family Neisseriaceae produce specific receptors to acquire iron from their host's lactoferrin and transferrin. Recently, putative Moraxella catarrhalis lactoferrin receptor genes and a third open reading frame (lbpB, lbpA, and orf3) were cloned and sequenced. We describe the preliminary characterization of isogenic mutants deficient in LbpB, LbpA, or Orf3 protein.
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页码：1517 / 1520
页数：4
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