Meaningful Improvement in Gait Speed in Hip Fracture Recovery

被引:44
作者
Alley, Dawn E. [1 ]
Hicks, Gregory E. [4 ]
Shardell, Michelle [1 ]
Hawkes, William [1 ]
Miller, Ram [1 ]
Craik, Rebecca L. [5 ]
Mangione, Kathleen K. [5 ]
Orwig, Denise [1 ]
Hochberg, Marc [2 ]
Resnick, Barbara [3 ]
Magaziner, Jay [1 ]
机构
[1] Univ Maryland, Sch Med, Dept Epidemiol & Publ Hlth, Baltimore, MD 21201 USA
[2] Univ Maryland, Sch Med, Dept Med, Baltimore, MD 21201 USA
[3] Univ Maryland, Sch Nursing, Baltimore, MD 21201 USA
[4] Univ Delaware, Dept Phys Therapy, Newark, DE USA
[5] Arcadia Univ, Dept Phys Therapy, Glenside, PA USA
基金
美国国家卫生研究院;
关键词
physical function; physical performance measures; mobility; minimum clinical difference; meaningful change; EXERCISE PLUS PROGRAM; OLDER; HEALTH; MOBILITY; DECLINE; DISABILITY; PREDICTS; SURVIVAL; TRIAL; LIFE;
D O I
10.1111/j.1532-5415.2011.03560.x
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
OBJECTIVES: To estimate meaningful improvements in gait speed observed during recovery from hip fracture and to evaluate the sensitivity and specificity of gait speed changes in detecting change in self-reported mobility. DESIGN: Secondary longitudinal data analysis from two randomized controlled trials SETTING: Twelve hospitals in the Baltimore, Maryland, area. PARTICIPANTS: Two hundred seventeen women admitted with hip fracture. MEASUREMENTS: Usual gait speed and self-reported mobility (ability to walk 1 block and climb 1 flight of stairs) measured 2 and 12 months after fracture. RESULTS: Effect size-based estimates of meaningful differences were 0.03 for small differences and 0.09 for substantial differences. Depending on the anchor (stairs vs walking) and method (mean difference vs regression), anchor-based estimates ranged from 0.10 to 0.17 m/s for small meaningful improvements and 0.17 to 0.26 m/s for substantial meaningful improvement. Optimal gait speed cutpoints yielded low sensitivity (0.39-0.62) and specificity (0.57-0.76) for improvements in self-reported mobility. CONCLUSION: Results from this sample of women recovering from hip fracture provide only limited support for the 0.10-m/s cut point for substantial meaningful change previously identified in community-dwelling older adults experiencing declines in walking abilities. Anchor-based estimates and cut points derived from receiver operating characteristic curve analysis suggest that greater improvements in gait speed may be required for substantial perceived mobility improvement in female hip fracture patients. Furthermore, gait speed change performed poorly in discriminating change in self-reported mobility. Estimates of meaningful change in gait speed may differ based on the direction of change (improvement vs decline) or between patient populations. J Am Geriatr Soc 59: 1650-1657, 2011.
引用
收藏
页码:1650 / 1657
页数:8
相关论文
共 32 条
[21]   Determining meaningful changes in gait speed after hip fracture [J].
Palombaro, Kerstin M. ;
Craik, Rebecca L. ;
Mangione, Kathleen K. ;
Tomlinson, James D. .
PHYSICAL THERAPY, 2006, 86 (06) :809-816
[22]   Magnitude and patterns of decline in health and function in 1 year affect subsequent 5-year survival [J].
Perera, S ;
Studenski, S ;
Chandler, JM ;
Guralnik, JM .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2005, 60 (07) :894-900
[23]   Meaningful change and responsiveness in common physical performance measures in older adults [J].
Perera, Subashan ;
Mody, Samir H. ;
Woodman, Ricbard C. ;
Studenski, Stephanie A. .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2006, 54 (05) :743-749
[24]   Evaluating the components of the Exercise Plus Program: rationale, theory and implementation [J].
Resnick, B ;
Magaziner, J ;
Orwig, D ;
Zimmerman, S .
HEALTH EDUCATION RESEARCH, 2002, 17 (05) :648-658
[25]   Testing the effectiveness of the exercise plus program in older women post-hip fracture [J].
Resnick, Barbara ;
Orwig, Denise ;
Yu-Yahiro, Janet ;
Hawkes, William ;
Shardell, Michelle ;
Hebel, J. Richard ;
Zimmerman, Sheryl ;
Golden, Justine ;
Werner, Michele ;
Magaziner, Jay .
ANNALS OF BEHAVIORAL MEDICINE, 2007, 34 (01) :67-76
[26]   Weighted estimating equations for longitudinal studies with death and non-monotone missing time-dependent covariates and outcomes [J].
Shardell, Michelle ;
Miller, Ram R. .
STATISTICS IN MEDICINE, 2008, 27 (07) :1008-1025
[27]   The effect of obesity combined with low muscle strength on decline in mobility in older persons: results from the InCHIANTI Study [J].
Stenholm, S. ;
Alley, D. ;
Bandinelli, S. ;
Griswold, M. E. ;
Koskinen, S. ;
Rantanen, T. ;
Guralnik, J. M. ;
Ferrucci, L. .
INTERNATIONAL JOURNAL OF OBESITY, 2009, 33 (06) :635-644
[28]   Joint Association of Obesity and Metabolic Syndrome With Incident Mobility Limitation in Older Men and Women-Results From the Health, Aging, and Body Composition Study [J].
Stenholm, Sari ;
Koster, Annemarie ;
Alley, Dawn E. ;
Houston, Denise K. ;
Kanaya, Alka ;
Lee, Jung Sun ;
Newman, Anne B. ;
Satterfield, Suzanne ;
Simonsick, Eleanor M. ;
Visser, Marjolein ;
Harris, Tamara B. ;
Ferrucci, Luigi .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2010, 65 (01) :84-92
[29]   Gait Speed and Survival in Older Adults [J].
Studenski, Stephanie ;
Perera, Subashan ;
Patel, Kushang ;
Rosano, Caterina ;
Faulkner, Kimberly ;
Inzitari, Marco ;
Brach, Jennifer ;
Chandler, Julie ;
Cawthon, Peggy ;
Connor, Elizabeth Barrett ;
Nevitt, Michael ;
Visser, Marjolein ;
Kritchevsky, Stephen ;
Badinelli, Stefania ;
Harris, Tamara ;
Newman, Anne B. ;
Cauley, Jane ;
Ferrucci, Luigi ;
Guralnik, Jack .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2011, 305 (01) :50-58
[30]   Meaningful Gait Speed Improvement During the First 60 Days Poststroke: Minimal Clinically Important Difference [J].
Tilson, Julie K. ;
Sullivan, Katherine J. ;
Cen, Steven Y. ;
Rose, Dorian K. ;
Koradia, Cherisha H. ;
Azen, Stanley P. ;
Duncan, Pamela W. .
PHYSICAL THERAPY, 2010, 90 (02) :196-208