Shedding light on corticosteroid-resistant type 2-high severe asthma

被引:5
|
作者
Chung, Kian Fan [1 ,2 ]
机构
[1] Imperial Coll London, Natl Heart & Lung Inst, Dovehouse St, London SW3 6LY, England
[2] Royal Brompton & Harefield NHS Trust, London, England
关键词
Asthma; type; 2; inflammation; corticosteroid resistance; eosinophils; INSENSITIVITY; INFLAMMATION;
D O I
10.1016/j.jaci.2018.11.002
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:89 / 90
页数:2
相关论文
共 50 条
  • [21] Immunologic Basis of Type 2 Biologics for Severe Asthma
    Sim, Soyoon
    Choi, Youngwoo
    Park, Hae-Sim
    IMMUNE NETWORK, 2022, 22 (06)
  • [22] Single-Cell and Population Transcriptomics Reveal Pan-epithelial Remodeling in Type 2-High Asthma
    Jackson, Nathan D.
    Everman, Jamie L.
    Chioccioli, Maurizio
    Feriani, Luigi
    Goldfarbmuren, Katherine C.
    Sajuthi, Satria P.
    Rios, Cydney L.
    Powell, Roger
    Armstrong, Michael
    Gomez, Joe
    Michel, Cole
    Eng, Celeste
    Oh, Sam S.
    Rodriguez-Santana, Jose
    Cicuta, Pietro
    Reisdorph, Nichole
    Burchard, Esteban G.
    Seibold, Max A.
    CELL REPORTS, 2020, 32 (01):
  • [23] Corticosteroid-resistant bronchial asthma is associated with increased c-fos expression in monocytes and T lymphocytes
    Lane, SJ
    Adcock, IM
    Richards, D
    Hawrylowicz, C
    Barnes, PJ
    Lee, TH
    JOURNAL OF CLINICAL INVESTIGATION, 1998, 102 (12): : 2156 - 2164
  • [24] High-resolution metabolomics to identify urine biomarkers in corticosteroid-resistant asthmatic children
    Park, Youngja H.
    Fitzpatrick, Anne M.
    Medriano, Carl Angelo
    Jones, Dean P.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2017, 139 (05) : 1518 - +
  • [25] Cluster analysis of sputum cytokine-high profiles reveals diversity in T(h) 2-high asthma patients
    Seys, Sven F.
    Scheers, Hans
    Van den Brande, Paul
    Marijsse, Gudrun
    Dilissen, Ellen
    Van den Bergh, Annelies
    Goeminne, Pieter C.
    Hellings, Peter W.
    Ceuppens, Jan L.
    Dupont, Lieven J.
    Bullens, Dominique M. A.
    RESPIRATORY RESEARCH, 2017, 18
  • [26] The high and lows of type 2 asthma and mouse models
    Fallon, Padraic G.
    Schwartz, Christian
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2020, 145 (02) : 496 - 498
  • [27] Type 2 Low Biomarker Stability and Exacerbations in Severe Uncontrolled Asthma
    Viinanen, Arja
    Aakko, Juhani
    Lassenius, Mariann I.
    Telg, Gunilla
    Nieminen, Kaisa
    Kaijala, Saara
    Lehtimaki, Lauri
    Kankaanranta, Hannu
    BIOMOLECULES, 2023, 13 (07)
  • [28] Baseline type 2 biomarker levels and response to tezepelumab in severe asthma
    Corren, Jonathan
    Tuyet-Hang Pham
    Gil, Esther Garcia
    Salapa, Kinga
    Ren, Pin
    Parnes, Jane R.
    Colice, Gene
    Griffiths, Janet M.
    ALLERGY, 2022, 77 (06) : 1786 - 1796
  • [29] Effects of biological therapies on patients with Type-2 high asthma and comorbid obesity
    Garg, Diya
    Que, Loretta G.
    Ingram, Jennifer L.
    FRONTIERS IN PHARMACOLOGY, 2024, 14
  • [30] Changes in Type 2 Biomarkers After Anti-IL5 Treatment in Patients With Severe Eosinophilic Asthma
    Jang, Jae-Hyuk
    Woo, Seong-Dae
    Lee, Youngsoo
    Kim, Chang-Keun
    Shin, Yoo Seob
    Ye, Young-Min
    Park, Hae-Sim
    ALLERGY ASTHMA & IMMUNOLOGY RESEARCH, 2021, 13 (02) : 330 - 338