Antibacterial phenolic components from Eriocaulon buergerianum

被引：31
作者：
Fang, Jing-Jing [1 ,2 ]
Yea, Guan [1 ]
Chen, Wen-Liang [2 ]
Zhao, Wei-Min [2 ]
机构：
[1] Cent Res Inst, Shanghai Pharmaceut Grp, Shanghai, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China
来源：
PHYTOCHEMISTRY | 2008年 / 69卷 / 05期
关键词：
Eriocaulon buergerianum; eriocaulaceae; xanthone; flavonoid; naphthopyranone; antibacterial activity; staphylococcus aureus (ATCC 25-923);
D O I：
10.1016/j.phytochem.2007.11.014
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Five phenolic components, 1, 3,6-trihydroxy-2,5,7-trimethoxyxanthone (1), 7,3'-dihydroxy-5,4',5'-trimethoxyisoflavone (2), toralactone-9- O-beta-D-glucopyranoside (3), patuletin-3-O-[2-O-E-feruloyl-beta-D-glucopyranosyl-(1 -> 6-p-D-glucopyranoside] (4), patuletin-3-O-[beta-D-glucopyranosyl-(l 1 -> 3)-2-O-E-caffeoyl-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranoside] (5), along with 19 known compounds were isolated from Eriocaulon buergerianum (Eriocaulaceae). Their structures were determined by spectroscopic and chemical methods. All 24 isolated compounds were tested against the pathogenic bacteria Staphylococcus aureus (ATCC 25923); as a result, 10 compounds were found to exhibit antibacterial activity with MICs ranging from 32 to 256 mu g/ml. (c) 2007 Elsevier Ltd. All rights reserved.
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页码：1279 / 1286
页数：8
相关论文
共 37 条
[1]  
AHMAD BT, 2006, AM J OPHTHALMOL, V142, P678
[2]  
ANDRADE FDP, 2002, BIOCH SYST ECOL, V30, P275
[3]  
ANDRADE FDP, 1999, PHYTOCHEMISTRY, V51, P411
[4]   Staphylococcus aureus:: A well-armed pathogen [J].
Archer, GL .
CLINICAL INFECTIOUS DISEASES, 1998, 26 (05) :1179-1181
[5]   CHEMICAL STUDIES ON THE EDIBLE PLANTS .5. FLAVONOL GLYCOSIDES IN LEAVES OF SPINACIA-OLERACEA [J].
ARITOMI, M ;
KOMORI, T ;
KAWASAKI, T .
PHYTOCHEMISTRY, 1985, 25 (01) :231-234
[6]   OMBUIN 3-SULFATE FROM FLAVERIA-CHLORAEFOLIA [J].
BARRON, D ;
IBRAHIM, RK .
PHYTOCHEMISTRY, 1988, 27 (07) :2362-2363
[7]   QUERCETAGETIN AND PATULETIN IN ERIOCAULON [J].
BATESMITH, EC ;
HARBORNE, JB .
PHYTOCHEMISTRY, 1969, 8 (06) :1035-+
[8]   FLAVONOIDS AND A PRENYLATED XANTHONE FROM CUDRANIA-COCHINCHINENSIS VAR GERONTOGEA [J].
CHANG, CH ;
LIN, CC ;
KADOTA, S ;
HATTORI, M ;
NAMBA, T .
PHYTOCHEMISTRY, 1995, 40 (03) :945-947
[9]   THE ANTHRAQUINONES OF HETERODERMIA-OBSCURATA [J].
COHEN, PA ;
TOWERS, GHN .
PHYTOCHEMISTRY, 1995, 40 (03) :911-915
[10]   Pigments of fungi.: Part 70.: Total synthesis of (R)-semixanthomegnin and the X-ray crystal structure of (±)-7-chloro-10-methoxy-3-methyl-3, 4-dihydro-1H-naphtho[2,3-c]pyran-1,6,9-trione [J].
Cotterill, AS ;
Donner, CD ;
Gill, M ;
White, JM .
AUSTRALIAN JOURNAL OF CHEMISTRY, 2003, 56 (01) :49-57
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