Masticatory function and related factors after oral oncological treatment: A 5-year prospective study

被引:32
作者
de Groot, Reilly J. [1 ]
Wetzels, Jan-Willem [1 ,2 ]
Merkx, Matthias A. W. [2 ]
Rosenberg, Antoine J. W. P. [1 ]
de Haan, Anton F. J. [3 ]
van der Bilt, Andries [1 ]
Abbink, Jan H. [1 ]
Speksnijder, Caroline M. [1 ,2 ,4 ,5 ]
机构
[1] Univ Med Ctr Utrecht, Dept Oral & Maxillofacial Surg & Special Dent Car, G05-122,POB 85-500, NL-3508 GA Utrecht, Netherlands
[2] Radboud Univ Nijmegen, Dept Oral & Maxillofacial Surg, Med Ctr, Nijmegen, Netherlands
[3] Radboud Univ Nijmegen, Sect Biostat, Dept Hlth Evidence, Med Ctr, Nijmegen, Netherlands
[4] Univ Med Ctr Utrecht, Julius Ctr Sci, Utrecht, Netherlands
[5] Univ Med Ctr Utrecht, Dept Head & Neck Surg Oncol, Ctr Canc, Utrecht, Netherlands
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2019年 / 41卷 / 01期
关键词
bite force; head and neck neoplasms; mastication; mixed model analysis; prospective cohort; QUALITY-OF-LIFE; TONGUE AND/OR FLOOR; HEAD; NECK; CANCER; PERFORMANCE; REHABILITATION; MOUTH; RECONSTRUCTION; MALIGNANCIES;
D O I
10.1002/hed.25445
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background Chewing ability is often compromised in patients with oral cancer. The aim of this study was to identify which factors affect masticatory performance in these patients. Methods Patients with primary oral cancer were assessed for up to 5 years after primary treatment. Healthy controls were assessed once. A mixed-model analysis was performed, with masticatory performance as outcome measure. Results A total of 123 patients were included in the study. Factors positively associated with masticatory performance were number of occlusal units (OU), having functional dentures, and maximum mouth opening (MMO). The impact of tumor location and maximum bite force (MBF) differed per assessment moment. Masticatory performance declined for up to 1 year but recovered at 5 years after treatment. Conclusion Masticatory performance in patients treated for oral cancer is affected by MBF, MMO, number of OU, and dental status. These should be the focus of posttreatment therapy.
引用
收藏
页码:216 / 224
页数:9
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