Clearance of Lormetazepam, Midazolam, and Their Conjugated Metabolites by Continuous Venovenous Hemofiltration During Prolonged Sedation in Critically Ill Patients With COVID-19-Associated Acute Respiratory Distress Syndrome

被引:1
作者
Shudofsky, Kimberly N. [1 ]
Janssen, Paddy K. C. [1 ,2 ]
Foudraine, Norbert [3 ]
le Noble, Jos L. M. L. [3 ,4 ]
机构
[1] VieCuri Med Ctr, Dept Clin Pharm, Venlo, Netherlands
[2] Maastricht Univ, Dept Clin Pharm & Toxicol, Med Ctr, Maastricht, Netherlands
[3] VieCuri Med Ctr, Dept Intens Care, Tegelseweg 210, NL-5912 BL Venlo, Netherlands
[4] UM, Dept Pharmacol & Toxicol, Maastricht, Netherlands
关键词
Conjugated metabolites; Continuous venovenous hemofiltration; COVID-19; Lormetazepam; Midazolam; Prolonged sedation; INTENSIVE-CARE PATIENTS; POPULATION PHARMACOKINETICS;
D O I
10.1002/jcph.2005
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:568 / 570
页数:3
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