Inhibition of eIF4E with ribavirin cooperates with common chemotherapies in primary acute myeloid leukemia specimens

被引:55
作者
Kraljacic, B. C. [1 ]
Arguello, M. [1 ]
Amri, A. [1 ]
Cormack, G. [1 ]
Borden, K. [1 ]
机构
[1] Univ Montreal, Dept Pathol & Cell Biol, IRIC, Montreal, PQ, Canada
基金
美国国家卫生研究院;
关键词
INITIATION-FACTOR EIF4E; ONCOGENIC TRANSFORMATION; CONTRIBUTES;
D O I
10.1038/leu.2011.57
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:1197 / 1200
页数:4
相关论文
共 12 条
[1]  
Abdel-Wahab Omar, 2010, F1000 Med Rep, V2, P55, DOI 10.3410/M2-55
[2]   Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin [J].
Assouline, Sarit ;
Culjkovic, Biljana ;
Cocolakis, Eftihia ;
Rousseau, Caroline ;
Beslu, Nathalie ;
Amri, Abdellatif ;
Caplan, Stephen ;
Leber, Brian ;
Roy, Denis-Claude ;
Miller, Wilson H., Jr. ;
Borden, Katherine L. B. .
BLOOD, 2009, 114 (02) :257-260
[3]   Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond? [J].
Borden, Katherine L. B. ;
Culjkovic-Kraljacic, Biljana .
LEUKEMIA & LYMPHOMA, 2010, 51 (10) :1805-1815
[4]   PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA [J].
Cohen, N ;
Sharma, M ;
Kentsis, A ;
Perez, JM ;
Strudwick, S ;
Borden, KLB .
EMBO JOURNAL, 2001, 20 (16) :4547-4559
[5]   Controlling gene expression through RNA regulons - The role of the eukaryotic translation initiation factor eIF4E [J].
Culjkovic, Biljana ;
Topisirovic, Ivan ;
Borden, Katherine L. B. .
CELL CYCLE, 2007, 6 (01) :65-69
[6]   Tumor-specific RNAi targeting eIF4E suppresses tumor growth, induces apoptosis and enhances cisplatin cytotoxicity in human breast carcinoma cells [J].
Dong, Ke ;
Wang, Rui ;
Wang, Xi ;
Lin, Fang ;
Shen, Jian-Jun ;
Gao, Ping ;
Zhang, Hui-Zhong .
BREAST CANCER RESEARCH AND TREATMENT, 2009, 113 (03) :443-456
[7]   Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap [J].
Kentsis, A ;
Topisirovic, I ;
Culjkovic, B ;
Shao, L ;
Borden, KLB .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (52) :18105-18110
[8]   Induction therapy for elderly patients with acute myeliod leukemia [J].
Martin, Mike G. ;
Abboud, Camille N. .
BLOOD REVIEWS, 2008, 22 (06) :311-320
[9]   Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities [J].
Topisirovic, I ;
Ruiz-Gutierrez, M ;
Borden, KLB .
CANCER RESEARCH, 2004, 64 (23) :8639-8642
[10]   Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis [J].
Topisirovic, I ;
Guzman, ML ;
McConnell, MJ ;
Licht, JD ;
Culjkovic, B ;
Neering, SJ ;
Jordan, CT ;
Borden, KLB .
MOLECULAR AND CELLULAR BIOLOGY, 2003, 23 (24) :8992-9002