Prevalence of bleeding symptoms among young adults in Saudi Arabia, a national survey

被引:4
作者
AlSaleh, Khalid A. [1 ]
Al-Numair, Nouf S. [2 ,3 ]
Alsuaiman, Ayman [4 ]
Zolaly, Mohammed [5 ]
Khojah, Osamah T. [6 ,7 ]
AlZahrani, Faisal M. [8 ]
Siddiqui, Khawar [9 ]
Al-Allaf, Faisal A. [10 ]
AlMomen, Abdulkareem [11 ]
Sajid, Raihan [12 ]
Owaidah, Tarek M. [13 ,14 ]
机构
[1] King Saud Univ, Coll Med, Dept Med, Riyadh, Saudi Arabia
[2] King Faisal Specialist Hosp & Res Ctr, Ctr Genom Med, Riyadh, Saudi Arabia
[3] Alfaisal Univ, Coll Med, POB 50927, Riyadh 11533, Saudi Arabia
[4] Alfaisal Univ, King Faisal Specialist Hosp, Res Ctr, Riyadh, Saudi Arabia
[5] Taibah Univ, Dept Pediat, Medina, Saudi Arabia
[6] King Saud Univ, Coll Med, Pathol Dept, Riyadh, Saudi Arabia
[7] Dr Sulaiman Alhabib Med Grp, Corp Med Affairs, Riyadh, Saudi Arabia
[8] King Saud Univ, Coll Med, Dept Pathol, Riyadh, Saudi Arabia
[9] Imam Abdulrahman Bin Faisal Univ, Coll Appl Med Sci, Dept Clin Lab Sci, Dammam, Saudi Arabia
[10] Alfaisal Univ, King Faisal Specialist Hosp, Dept Stat, Riyadh, Saudi Arabia
[11] Umm Al Qura Univ, Fac Med, Dept Med Genet, Mecca, Saudi Arabia
[12] Alfaisal Univ, Dept Pathol, Riyadh, Saudi Arabia
[13] King Faisal Specialist Hosp & Res Ctr, Dept Pathol & Lab Med, Riyadh, Saudi Arabia
[14] Alfaisal Univ, Riyadh, Saudi Arabia
关键词
bleeding; coagulation; inherited; VON-WILLEBRAND-DISEASE; DISORDERS; QUESTIONNAIRE; MANAGEMENT; TYPE-1; DIAGNOSIS; IMPACT;
D O I
10.1097/MD.0000000000027513
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Prevalence of bleeding disorders vary due to several factors including geographical location. Mild bleeding disorders can lead to iron deficiency, morbidity, and in severe cases mortality. Quantification of haemorrhagic symptoms is a key component in management of bleeding disorders and a challenging task for clinicians. An abridged version of MCMDM-1vWD questionnaire with validated Arabic translation was used to quantify bleeding disorders in adult students (n = 1138) in 4 different regions of Kingdom of Saudi Arabia. Statistical analysis was performed to indicate gender disparity and prevalence. 74.5% of respondents answered at least 1 question with affirmation, with 32.3% affected in Riyadh showing the highest prevalence and 14.03% affected in Dammam showing the least prevalence (P-value < .001). Gender-wise, higher prevalence of bleeding disorders in females 54.9% than in males 45.1% was observed (P-value .01). Epistaxis prevalence was significantly higher in males 30.7% vs 23.2% in females (P-value .0004), while cutaneous symptoms were reported significantly more by female participants 29.7% vs 12.3% in males (P-value < .001). Menorrhagia was reported by 28% of females, with heavy bleeding experienced by 57.6% female participants for 7 days. The current study signifies the ethnic distribution and gender disparity of mild bleeding disorders, and highlights the need for national surveillance system in order to improve management of patients with bleeding disorders.
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页数:7
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