High-flow nasal cannula as a device to provide continuous positive airway pressure in infants

被引：121

作者：

Spence, K. L.

Murphy, D.

Kilian, C.

McGonigle, R.

Kilani, R. A.

机构：

[1] Washington Univ, St Louis Childrens Hosp, Sch Med, Edward Mallinckrodt Dept Pediat,Div Newborn Med, St Louis, MO 63110 USA

[2] Univ Missouri, Childrens Mercy Hosp, Dept Pediat, Kansas City, MO 64108 USA

来源：

JOURNAL OF PERINATOLOGY | 2007年 / 27卷 / 12期

关键词：

CPAP; high-flow nasal cannula; newborn;

D O I：

10.1038/sj.jp.7211828

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: To measure the intrapharyngeal pressure ( IPP) generated by high-flow nasal cannula ( HFNC) at varying flow rates up to 51 min(-1). Study Design: We studied 14 infants on HFNC or NCPAP using IPP manometry to measure the IPP generated at flows of 1, 2, 3, 4 and 51 min(-1). Result: On average flow rates of 1, 2, 3, 4 and 51 min(-1) generated an IPP ( cm of H2O) of 1.70 +/- 0.34, 1.75 +/- 0.2, 2.62 +/- 0.28, 3.78 +/- 0.44 and 4.84 +/- 0.51 respectively. Conclusion: HFNC delivers significant IPP and is potentially a well-tolerated and viable option to provide CPAP at flows of >= 3 min(-1) in infants with respiratory distress.

引用

页码：772 / 775

页数：4

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